Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo model
about
Discovery of 2-Alkyl-1-arylsulfonylprolinamides as 11β-Hydroxysteroid Dehydrogenase Type 1 InhibitorsSubstrate binding process and mechanistic functioning of type 1 11β-hydroxysteroid dehydrogenase from enhanced sampling methods.11β-Hydroxysteroid dehydrogenase type 1: relevance of its modulation in the pathophysiology of obesity, the metabolic syndrome and type 2 diabetes mellitus.Novel small molecule 11β-HSD1 inhibitor from the endophytic fungus Penicillium commune.11beta-hydroxysteroid dehydrogenase type 1 inhibitors: a review of recent patents.Crystal structures of 11β-hydroxysteroid dehydrogenase type 1 and their use in drug discovery.On-column ligand exchange for structure-based drug design: a case study with human 11β-hydroxysteroid dehydrogenase type 1.
P2860
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P2860
Discovery of novel, potent benzamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) exhibiting oral activity in an enzyme inhibition ex vivo model
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@ast
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@en
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@nl
type
label
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@ast
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@en
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@nl
prefLabel
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@ast
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@en
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@nl
P2093
P3181
P356
P1476
Discovery of novel, potent ben ...... nzyme inhibition ex vivo model
@en
P2093
Athena Sudom
Daqing Sun
Dustin McMinn
Jay P Powers
Jinsong Liu
Juan C Jaen
Lisa D Julian
Mario Monshouwer
Michael DeGraffenreid
P304
P3181
P356
10.1021/JM800310G
P407
P577
2008-07-10T00:00:00Z