Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
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Three decades of beta-lactamase inhibitorsThe Chemical Biology of Human Metallo-β-Lactamase Fold ProteinsThe Structure of the Dizinc Subclass B2 Metallo- -Lactamase CphA Reveals that the Second Inhibitory Zinc Ion Binds in the Histidine SiteSelective Inhibitors of the JMJD2 Histone Demethylases: Combined Nondenaturing Mass Spectrometric Screening and Crystallographic ApproachesStructural Insights into the Subclass B3 Metallo- -Lactamase SMB-1 and the Mode of Inhibition by the Common Metallo- -Lactamase Inhibitor MercaptoacetateCrystal Structure of the Mobile Metallo- -Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the Role of Gln157Solution structures of the Bacillus cereus metallo-β-lactamase BcII and its complex with the broad spectrum inhibitor R -thiomandelic acidEvolving carbapenemases: can medicinal chemists advance one step ahead of the coming storm?New β-lactamase inhibitors: a therapeutic renaissance in an MDR world.Complete ¹H, ¹⁵N, and ¹³C resonance assignments of Bacillus cereus metallo-β-lactamase and its complex with the inhibitor R-thiomandelic acid.QM/MM studies of monozinc β-lactamase CphA suggest that the crystal structure of an enzyme-intermediate complex represents a minor pathway.Crystal structure of human persulfide dioxygenase: structural basis of ethylmalonic encephalopathy.Structural Basis of Metallo-β-Lactamase Inhibition by Captopril StereoisomersAzolylthioacetamide: A Highly Promising Scaffold for the Development of Metallo-β-lactamase Inhibitors.Amino Acid Thioester Derivatives: A Highly Promising Scaffold for the Development of Metallo-β-lactamase L1 Inhibitors.Carbapenemases in Klebsiella pneumoniae and other Enterobacteriaceae: an evolving crisis of global dimensionsTriazolylthioacetamide: A Valid Scaffold for the Development of New Delhi Metallo-β-Lactmase-1 (NDM-1) InhibitorsCross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes.New β-phospholactam as a carbapenem transition state analog: Synthesis of a broad-spectrum inhibitor of metallo-β-lactamasesAn Update on the Status of Potent Inhibitors of Metallo-β-Lactamases.Targeting metallo-β-lactamase enzymes in antibiotic resistance.Fragment-based inhibitor discovery against β-lactamaseA variety of roles for versatile zinc in metallo-β-lactamases.Progress toward inhibitors of metallo-β-lactamases.New Delhi metallo-β-lactamase-1: structure, inhibitors and detection of producers.Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-β-Lactamase Identified from a Functional Metagenomic Study.Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem.Structural Insights into TMB-1 and the Role of Residues 119 and 228 in Substrate and Inhibitor Binding.Monitoring conformational changes in the NDM-1 metallo-β-lactamase by 19F NMR spectroscopy.19 F-NMR Reveals the Role of Mobile Loops in Product and Inhibitor Binding by the São Paulo Metallo-β-Lactamase.Assay platform for clinically relevant metallo-β-lactamases.Studying the active-site loop movement of the São Paolo metallo-β-lactamase-1†Electronic supplementary information (ESI) available: Procedures for protein expression and purification, 19F-labelling, crystallisation, data collection, and structure deProbing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases.Synthesis of (2-mercaptoacetyl)-L-[2-14 C]tryptophan as a selective metallo-β-lactamase inhibitor via [2-14 C]indole based on chiral pool strategy.The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters.Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases.Rhodanine as a Potent Scaffold for the Development of Broad-Spectrum Metallo-β-lactamase Inhibitors.Crystallographic analyses of isoquinoline complexes reveal a new mode of metallo-β-lactamase inhibition.Structural and Kinetic Studies of the Potent Inhibition of Metallo-β-lactamases by 6-Phosphonomethylpyridine-2-carboxylates.
P2860
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P2860
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@ast
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@en
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@nl
type
label
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@ast
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@en
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@nl
prefLabel
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@ast
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@en
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@nl
P2093
P50
P356
P1476
Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols
@en
P2093
Benoît M R Liénard
Christian Damblon
Cyril Papamicael
Gordon C K Roberts
P304
P356
10.1039/B802311E
P50
P577
2008-07-07T00:00:00Z