Explaining an Unusually Fast Parasitic Enzyme: Folate Tail-Binding Residues Dictate Substrate Positioning and Catalysis in Cryptosporidium hominis Thymidylate Synthase † ‡
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Mg 2+ Binds to the Surface of Thymidylate Synthase and Affects Hydride Transfer at the Interior Active SiteFirst Three-Dimensional Structure of Toxoplasma gondii Thymidylate Synthase–Dihydrofolate Reductase: Insights for Catalysis, Interdomain Interactions, and Substrate ChannelingExploring novel strategies for AIDS protozoal pathogens: α-helix mimetics targeting a key allosteric protein–protein interaction in C. hominis thymidylate synthase-dihydrofolate reductase (TS-DHFR)Cryptosporidium: genomic and biochemical featuresStructural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase.
P2860
Explaining an Unusually Fast Parasitic Enzyme: Folate Tail-Binding Residues Dictate Substrate Positioning and Catalysis in Cryptosporidium hominis Thymidylate Synthase † ‡
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@ast
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@en
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@nl
type
label
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@ast
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@en
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@nl
prefLabel
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@ast
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@en
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@nl
P2093
P2860
P356
P1433
P1476
Explaining an Unusually Fast P ...... minis Thymidylate Synthase † ‡
@en
P2093
Karen S Anderson
Melissa A Vargo
W Edward Martucci
P2860
P304
P356
10.1021/BI800466Z
P407
P577
2008-08-26T00:00:00Z