Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5
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IRF7: activation, regulation, modification and functionActivation of interferon regulatory factor 5 by site specific phosphorylationThe crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factorAn IRF5 Decoy Peptide Reduces Myocardial Inflammation and Fibrosis and Improves Endothelial Cell Function in Tight-Skin MiceClusters of isoleucine, leucine, and valine side chains define cores of stability in high-energy states of globular proteins: Sequence determinants of structure and stability.Toll-like receptor signaling in cell proliferation and survivalStructural insights into interferon regulatory factor activation.Identification of a novel in vivo virus-targeted phosphorylation site in interferon regulatory factor-3 (IRF3)IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.Mapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphomaProtein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells.IKKβ is an IRF5 kinase that instigates inflammationInterferon regulatory factors: critical mediators of human lupus.A conserved region within interferon regulatory factor 5 controls breast cancer cell migration through a cytoplasmic and transcription-independent mechanismThe use of analytical sedimentation velocity to extract thermodynamic linkage.TRIpartite motif 21 (TRIM21) differentially regulates the stability of interferon regulatory factor 5 (IRF5) isoforms.Differential requirement of histone acetylase and deacetylase activities for IRF5-mediated proinflammatory cytokine expression.Characterization of common carp (Cyprinus carpio L.) interferon regulatory factor 5 (IRF5) and its expression in response to viral and bacterial challenges.Understanding Transcription Factor Regulation by Integrating Gene Expression and DNase I Hypersensitive Sites.Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker DomainToward an orofacial gene regulatory network.RETRACTED: The COP9 signalosome interacts with and regulates interferon regulatory factor 5 protein stability.PPE38 of Mycobacterium marinum triggers the cross-talk of multiple pathways involved in the host response, as revealed by subcellular quantitative proteomics.Structural basis for concerted recruitment and activation of IRF-3 by innate immune adaptor proteins.Rotavirus NSP1 mediates degradation of interferon regulatory factors through targeting of the dimerization domainBeneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis.Mitogen-activated protein kinase-mediated licensing of interferon regulatory factor 3/7 reinforces the cell response to virusInterferon regulatory factor 5 in the pathogenesis of systemic lupus erythematosus.Epigenetics and the IRFs: a complex interplay in the control of immunity and autoimmunity.Disrupted IRF6-NME1/2 Complexes as a Cause of Cleft Lip/Palate.An oligodeoxynucleotide with AAAG repeats significantly attenuates burn-induced systemic inflammatory responses via inhibiting interferon regulatory factor 5 pathwayStructural Basis of Intracellular TGF-β Signaling: Receptors and Smads.Pestivirus Npro Directly Interacts with Interferon Regulatory Factor 3 Monomer and Dimer.Four Promoters of IRF5 Respond Distinctly to Stimuli and are Affected by Autoimmune-Risk PolymorphismsBiallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation.Genetic variants of interferon regulatory factor 5 associated with chronic hepatitis B infection.Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.Corrected and Republished from: The COP9 Signalosome Interacts with and Regulates Interferon Regulatory Factor 5 Protein Stability.Assembly of human C-terminal Binding Protein (CtBP) into tetramers.
P2860
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P2860
Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Insights into interferon regul ...... stal structure of dimeric IRF5
@ast
Insights into interferon regul ...... stal structure of dimeric IRF5
@en
Insights into interferon regul ...... stal structure of dimeric IRF5
@nl
type
label
Insights into interferon regul ...... stal structure of dimeric IRF5
@ast
Insights into interferon regul ...... stal structure of dimeric IRF5
@en
Insights into interferon regul ...... stal structure of dimeric IRF5
@nl
prefLabel
Insights into interferon regul ...... stal structure of dimeric IRF5
@ast
Insights into interferon regul ...... stal structure of dimeric IRF5
@en
Insights into interferon regul ...... stal structure of dimeric IRF5
@nl
P2093
P2860
P921
P3181
P356
P1476
Insights into interferon regul ...... stal structure of dimeric IRF5
@en
P2093
Celia A Schiffer
Hema Srinath
John J Correia
Katherine A Fitzgerald
Suvana S Lam
Weijun Chen
William E Royer
Zhaozhao Jiang
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1496
P577
2008-11-01T00:00:00Z
P5875
P6179
1026894468