Structure of Human Prostasin, a Target for the Regulation of Hypertension
about
Mechanism of the Anticoagulant Activity of Thrombin Mutant W215A/E217AStabilization of the E* Form Turns Thrombin into an AnticoagulantCrystal structure of prethrombin-1Crystallographic and Kinetic Evidence of Allostery in a Trypsin-like ProteaseMutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors.Prostasin may contribute to chemoresistance, repress cancer cells in ovarian cancer, and is involved in the signaling pathways of CASP/PAK2-p34/actin.Evidence of the E*-E equilibrium from rapid kinetics of Na+ binding to activated protein C and factor Xa.Allostery in trypsin-like proteases suggests new therapeutic strategies.Prostasin: An Epithelial Sodium Channel Regulator.Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic ProteasesPSP94, an upstream signaling mediator of prostasin found highly elevated in ovarian cancer.Conformational selection in trypsin-like proteases.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Membrane-anchored serine proteases in health and disease.Serine proteases.Hepatocyte growth factor activator (HGFA): molecular structure and interactions with HGFA inhibitor-1 (HAI-1).Protein conformational plasticity and complex ligand-binding kinetics explored by atomistic simulations and Markov models.
P2860
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P2860
Structure of Human Prostasin, a Target for the Regulation of Hypertension
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@ast
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@en
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@nl
type
label
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@ast
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@en
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@nl
prefLabel
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@ast
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@en
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@nl
P2093
P2860
P356
P1476
Structure of Human Prostasin, a Target for the Regulation of Hypertension
@en
P2093
Allison M Montalvo
Bradley W Thomas
Dawn L Hall
Hua-Poo Su
Jennifer M Shipman
John C Reid
Keith W Rickert
Noel J Byrne
Paul Kelley
Paul L Darke
P2860
P304
P356
10.1074/JBC.M805262200
P407
P577
2008-12-12T00:00:00Z