Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
about
The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymeraseEnzymology of RNA cap synthesisShutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common ThemesPerspective of Use of Antiviral Peptides against Influenza VirusThe polymerase of negative-stranded RNA virusesCrystal structure of the RNA-dependent RNA polymerase from influenza C virus.Influenza a virus assembly intermediates fuse in the cytoplasmNucleoside Monophosphate Complex Structures of the Endonuclease Domain from the Influenza Virus Polymerase PA Subunit Reveal the Substrate Binding Site inside the Catalytic CenterStructural insight into the essential PB1–PB2 subunit contact of the influenza virus RNA polymeraseStructure of YqgQ protein fromBacillus subtilis, a conserved hypothetical proteinThe Crystal Structure of Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein Nsp1 Reveals a Novel Metal-Dependent NucleaseBunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral Cap-Dependent TranscriptionThe N-Terminal Domain of the Arenavirus L Protein Is an RNA Endonuclease Essential in mRNA TranscriptionCap binding and immune evasion revealed by Lassa nucleoprotein structureStructural and Biochemical Basis for Development of Influenza Virus Inhibitors Targeting the PA EndonucleaseStructural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza pH1N1 (2009) PolymeraseOrganization of the influenza virus replication machineryCrystal structure of Prp8 reveals active site cavity of the spliceosomeStructural and Functional Characterization of K339T Substitution Identified in the PB2 Subunit Cap-binding Pocket of Influenza A VirusCrystallographic Fragment Screening and Structure-Based Optimization Yields a New Class of Influenza Endonuclease InhibitorsThe N-Terminal Domain of PA from Bat-Derived Influenza-Like Virus H17N10 Has Endonuclease ActivityConformational polymorphism of m7GTP in crystal structure of the PB2 middle domain from human influenza A virusComparative structural and functional analysis of orthomyxovirus polymerase cap-snatching domainsHigh-Resolution Structure of the N-Terminal Endonuclease Domain of the Lassa Virus L Polymerase in Complex with Magnesium Ions3-Hydroxyquinolin-2(1 H )-ones As Inhibitors of Influenza A EndonucleaseStructural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1The Influenza Virus Polymerase Complex: An Update on Its Structure, Functions, and Significance for Antiviral Drug DesignNew small-molecule drug design strategies for fighting resistant influenza AUpolu virus and Aransas Bay virus, two presumptive bunyaviruses, are novel members of the family OrthomyxoviridaeTracking the Evolution of Polymerase Genes of Influenza A Viruses during Interspecies Transmission between Avian and Swine HostsGreen tea catechins inhibit the endonuclease activity of influenza A virus RNA polymeraseIdentification of a PA-binding peptide with inhibitory activity against influenza A and B virus replicationHeat shock protein 70 inhibits the activity of Influenza A virus ribonucleoprotein and blocks the replication of virus in vitro and in vivoAnti-influenza activity of marchantins, macrocyclic bisbibenzyls contained in liverwortsMutational analysis of the binding pockets of the diketo acid inhibitor L-742,001 in the influenza virus PA endonucleaseA Novel Antiviral Target Structure Involved in the RNA Binding, Dimerization, and Nuclear Export Functions of the Influenza A Virus NucleoproteinIdentification of high-affinity PB1-derived peptides with enhanced affinity to the PA protein of influenza A virus polymeraseInteractome analysis of the influenza A virus transcription/replication machinery identifies protein phosphatase 6 as a cellular factor required for efficient virus replication.Phenyl substituted 4-hydroxypyridazin-3(2H)-ones and 5-hydroxypyrimidin-4(3H)-ones: inhibitors of influenza A endonuclease.Polymerase discordance in novel swine influenza H3N2v constellations is tolerated in swine but not human respiratory epithelial cells
P2860
Q21089768-E69BC8FF-A74E-43DC-9A46-FF1E94C0C469Q24567974-A31ABFAA-8509-4ADD-97B2-75331B5E686AQ26752361-9353EB4B-CAE0-4C6C-86C2-115D3799BDB3Q26780434-A6E1C7A2-F3E9-447D-8F24-186FA4FDCC30Q26824373-3A3E2403-8173-4F0E-A072-4460B80227B7Q27315161-720F40EC-E9B2-490C-BEC8-49D201D74889Q27330190-8D23CDFF-2C6B-4882-A7A7-7EA987C7C075Q27646520-3B020FDA-D175-4BB0-8BD8-DCFFB99DBF53Q27655568-8081127F-287B-47D0-822E-E28A4988AF0FQ27658888-B2E37A6B-9B95-4C83-94F2-E3DE90851FA1Q27660720-1503BFBF-0DD8-40AC-A685-5939E9B3CBC0Q27664646-45A0943F-6BD7-421E-8695-7E3C5CAB72C8Q27664647-C30A5133-E181-4B59-AC1A-67558164B15FQ27665958-AEA622D1-31D7-4214-857F-5013FEEF714EQ27671357-B23F5809-1CCC-4D6A-9074-2E8E6883F158Q27671365-C06ACCCE-FEE0-46C7-952A-A64F9CA407CDQ27675228-1FE03A7C-548F-49D4-90A2-8CB2C4CE7AC9Q27676016-5164DE85-FC46-42E5-A7E4-7A9D94A7255CQ27676615-D5BF1B96-8AB8-456F-8E2A-408516FF0178Q27679805-0EE3E2C5-4A24-4D39-9380-7FECD781547DQ27680700-0CC84B5C-CB54-457E-933B-0B5A6CF62C4DQ27680799-02CA8A0C-099B-4F10-9DA5-8ACA061F4F26Q27681434-96964655-5F75-40CE-9741-FC6C53815D76Q27681674-A7BA8A79-0F61-4C5B-96FB-CE3E72EC6185Q27684365-B05C67AF-4CBB-4458-B3D6-B32B11E18C66Q27684927-3675E34B-CF69-4A41-A110-61A86AB4383FQ28071809-517E0100-1B1E-467A-A726-56AC7D0A26BBQ28080554-B537DD0E-FCDD-484C-85BA-285BB000869CQ28308081-DC0788FB-4DD2-4C06-8B4F-443981AB877EQ28354200-F17CC3BA-D6D8-41C5-808E-AFF748B00FD3Q28471610-D2ECEFD7-C553-4AC6-BA88-AB48330E17AFQ28476315-9D21898D-3231-4225-8A78-55186ACB987FQ28477264-319179E0-FFB4-4040-8EC5-FAB3AD3FFB56Q28478205-3D489C74-68E3-487D-AC48-A556DC6EF6F9Q28534627-9BA09F19-DD63-46E7-9951-43392454880DQ28546866-615CF946-1E2D-44FA-BAB3-97ED0955D7EFQ28743238-845E0D54-4085-4EE3-9C35-576601987371Q30366402-A62BD1BB-003B-42A9-B93A-53A8C6122C6AQ30366846-D00BB1BE-6F20-497C-8B8B-B4A062BAA167Q30367947-7B83FF02-F3BC-4E80-B9B9-04DEDB1FD16F
P2860
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Crystal structure of an avian ...... ls an endonuclease active site
@ast
Crystal structure of an avian ...... ls an endonuclease active site
@en
Crystal structure of an avian ...... ls an endonuclease active site
@en-gb
Crystal structure of an avian ...... ls an endonuclease active site
@nl
type
label
Crystal structure of an avian ...... ls an endonuclease active site
@ast
Crystal structure of an avian ...... ls an endonuclease active site
@en
Crystal structure of an avian ...... ls an endonuclease active site
@en-gb
Crystal structure of an avian ...... ls an endonuclease active site
@nl
prefLabel
Crystal structure of an avian ...... ls an endonuclease active site
@ast
Crystal structure of an avian ...... ls an endonuclease active site
@en
Crystal structure of an avian ...... ls an endonuclease active site
@en-gb
Crystal structure of an avian ...... ls an endonuclease active site
@nl
P2093
P50
P3181
P356
P1433
P1476
Crystal structure of an avian ...... ls an endonuclease active site
@en
P2093
Puwei Yuan
Xiaojing He
Yingfang Liu
Zhiyong Lou
P2888
P304
P3181
P356
10.1038/NATURE07720
P407
P577
2009-04-16T00:00:00Z
P5875
P6179
1052986587