Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
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Insights into enzymatic halogenation from computational studiesFlavoenzymes: versatile catalysts in biosynthetic pathwaysThe ternary complex of PrnB (the second enzyme in the pyrrolnitrin biosynthesis pathway), tryptophan, and cyanide yields new mechanistic insights into the indolamine dioxygenase superfamilyA Structure-Guided Switch in the Regioselectivity of a Tryptophan HalogenaseStructure and biocatalytic scope of thermophilic flavin-dependent halogenase and flavin reductase enzymesBiosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pairOrigin and evolution of peptide-modifying dioxygenases and identification of the wybutosine hydroxylase/hydroperoxidase.Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis.Regioselective arene halogenation using the FAD-dependent halogenase RebH.Enzymatic halogenation of tryptophan on a gram scale.Directed Evolution of RebH for Catalyst-Controlled Halogenation of Indole C-H BondsForm follows function: structural and catalytic variation in the class a flavoprotein monooxygenases.A Fivefold Parallelized Biosynthetic Process Secures Chlorination of Armillaria mellea (Honey Mushroom) Toxins.Enzymatic Halogenation and Dehalogenation Reactions: Pervasive and Mechanistically Diverse.Specific Enzymatic Halogenation-From the Discovery of Halogenated Enzymes to Their Applications In Vitro and In Vivo.Enzymatic site-selectivity enabled by structure-guided directed evolution.Enzymatic Halogenation: A Timely Strategy for Regioselective C-H Activation.Purification and crystallographic analysis of a FAD-dependent halogenase from Streptomyces sp. JCM9888.Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenaseIntegrating carbon-halogen bond formation into medicinal plant metabolism.Understanding Flavin-Dependent Halogenase Reactivity via Substrate Activity Profiling.Aromatic Halogenation by Using Bifunctional Flavin Reductase-Halogenase Fusion Enzymes.Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.A flavin-dependent halogenase from metagenomic analysis prefers bromination over chlorination.Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes.Understanding and Improving the Activity of Flavin-Dependent Halogenases via Random and Targeted Mutagenesis.Two-Component FAD-Dependent Monooxygenases: Current Knowledge and Biotechnological Opportunities
P2860
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P2860
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@ast
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@en
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@nl
type
label
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@ast
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@en
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@nl
prefLabel
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@ast
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@en
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@nl
P2093
P2860
P1476
Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan
@en
P2093
Julia Herrmann
Karl-Heinz van Pée
Katja Ihlefeld
Khim Leang
Walter De Laurentis
Xiaofeng Zhu
P2860
P356
10.1016/J.JMB.2009.06.008
P407
P577
2009-08-07T00:00:00Z