MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity
about
Factors of the lectin pathway of complement activation and their clinical associations in neonatesMASP1 mutations in patients with facial, umbilical, coccygeal, and auditory findings of Carnevale, Malpuech, OSA, and Michels syndromesPaths reunited: Initiation of the classical and lectin pathways of complement activationPutting the structure into complementStructure-Function Analysis of Grass Clip Serine Protease Involved in Drosophila Toll Pathway ActivationQuantitative Characterization of the Activation Steps of Mannan-binding Lectin (MBL)-associated Serine Proteases (MASPs) Points to the Central Role of MASP-1 in the Initiation of the Complement Lectin PathwayMonospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2The Serine Protease Domain of MASP-3: Enzymatic Properties and Crystal Structure in Complex with EcotinCalcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1rComplement: a key system for immune surveillance and homeostasisTranscriptome analysis indicates an enhanced activation of adaptive and innate immunity by chlamydia-infected murine epithelial cells treated with interferon γ.Cleavage of kininogen and subsequent bradykinin release by the complement component: mannose-binding lectin-associated serine protease (MASP)-1Effects of MASP-1 of the complement system on activation of coagulation factors and plasma clot formation.Humoral pattern recognition and the complement system.The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American womenEssential role of complement mannose-binding lectin-associated serine proteases-1/3 in the murine collagen antibody-induced model of inflammatory arthritis.MASP-1 Induced Clotting--The First Model of Prothrombin Activation by MASP-1.Novel MASP1 mutations are associated with an expanded phenotype in 3MC1 syndromeMASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linkedDisease-causing mutations in genes of the complement system.A journey through the lectin pathway of complement-MBL and beyond.Deconstructing the Lectin Pathway in the Pathogenesis of Experimental Inflammatory Arthritis: Essential Role of the Lectin Ficolin B and Mannose-Binding Protein-Associated Serine Protease 2.The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond.The complement factor H-related proteins.Mechanisms of mannose-binding lectin-associated serine proteases-1/3 activation of the alternative pathway of complement.Oligomerization of Mannan-binding Lectin Dictates Binding Properties and Complement Activation.Deposition of mannose-binding lectin and ficolins and activation of the lectin pathway of complement on the surface of polyurethane tubing used for cardiopulmonary bypass.Flexibility in Mannan-Binding Lectin-Associated Serine Proteases-1 and -2 Provides Insight on Lectin Pathway Activation.Polyphosphate is a novel cofactor for regulation of complement by a serpin, C1 inhibitor.Mannan binding lectin-associated serine protease 1 is induced by hepatitis C virus infection and activates human hepatic stellate cells.The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech.Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in serum and stoichiometry of lectin pathway components.MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model.Extensive Basal Level Activation of Complement Mannose-Binding Lectin-Associated Serine Protease-3: Kinetic Modeling of Lectin Pathway Activation Provides Possible Mechanism.Leishmania donovani Inhibitor of Serine Peptidases 2 Mediated Inhibition of Lectin Pathway and Upregulation of C5aR Signaling Promote Parasite Survival inside Host.SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties.Complement in the Initiation and Evolution of Rheumatoid Arthritis.Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1Be on Target: Strategies of Targeting Alternative and Lectin Pathway Components in Complement-Mediated Diseases
P2860
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P2860
MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@ast
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@en
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@nl
type
label
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@ast
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@en
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@nl
prefLabel
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@ast
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@en
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@nl
P2093
P3181
P356
P1476
MASP-1, a promiscuous compleme ...... basis of its broad specificity
@en
P2093
Edina Sebestyén
József Dobó
László Beinrohr
P304
P3181
P356
10.4049/JIMMUNOL.0901141
P407
P577
2009-07-15T00:00:00Z