Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism - Test2 - elhamkhani - TriplyDB

Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism

Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism

http://www.wikidata.org/entity/Q27658021

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Pathogen roid rage: cholesterol utilization by Mycobacterium tuberculosis A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism Activity of 3-ketosteroid 9α-hydroxylase (KshAB) indicates cholesterol side chain and ring degradation occur simultaneously in Mycobacterium tuberculosis Characterization of an oxidoreductase from the arylamine N-acetyltransferase operon in Mycobacterium smegmatis The Lid Domain of the MCP Hydrolase DxnB2 Contributes to the Reactivity toward Recalcitrant PCB Metabolites A Substrate-Assisted Mechanism of Nucleophile Activation in a Ser–His–Asp Containing C–C Bond Hydrolase Structure of arylamine N-acetyltransferase from Mycobacterium tuberculosis determined by cross-seeding with the homologous protein from M. marinum: triumph over adversity Shrinking the FadE proteome of Mycobacterium tuberculosis: insights into cholesterol metabolism through identification of an α2β2 heterotetrameric acyl coenzyme A dehydrogenase family Pathway profiling in Mycobacterium tuberculosis: elucidation of cholesterol-derived catabolite and enzymes that catalyze its metabolism Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars Catabolism and biotechnological applications of cholesterol degrading bacteria.Accurate macromolecular crystallographic refinement: incorporation of the linear scaling, semiempirical quantum-mechanics program DivCon into the PHENIX refinement package Inhibition of the M. tuberculosis 3β-hydroxysteroid dehydrogenase by azasteroids.Cholesterol catabolism as a therapeutic target in Mycobacterium tuberculosis.The tuberculosis drug discovery and development pipeline and emerging drug targets.Investigation of the mycobacterial enzyme HsaD as a potential novel target for anti-tubercular agents using a fragment-based drug design approach.The Minimal Unit of Infection: Mycobacterium tuberculosis in the Macrophage.Bacterial degradation of bile salts.Adventures in Rhodococcus - from steroids to explosives.The Mycobacterium tuberculosis cytochromes P450: physiology, biochemistry & molecular intervention.Updating and curating metabolic pathways of TB.3-Ketosteroid 9α-hydroxylase enzymes: Rieske non-heme monooxygenases essential for bacterial steroid degradation.Tuberculosis drug discovery and emerging targets.Genome-wide bioinformatics analysis of steroid metabolism-associated genes in Nocardioides simplex VKM Ac-2033D.Cholesterol metabolism: a potential therapeutic target in Mycobacteria.Deciphering the transcriptional regulation of cholesterol catabolic pathway in mycobacteria: identification of the inducer of KstR repressor.Structural and biochemical characterisation of Archaeoglobus fulgidus esterase reveals a bound CoA molecule in the vicinity of the active site.Characterization of the KstR2 regulator responsible of the lower cholesterol degradative pathway in Mycobacterium smegmatis.Cyclipostins and Cyclophostin analogs as promising compounds in the fight against tuberculosis.The essential function of genes for a hydratase and an aldehyde dehydrogenase for growth of Pseudomonas sp. strain Chol1 with the steroid compound cholate indicates an aldolytic reaction step for deacetylation of the side chain Detection of Delta-like 1 ligand for the diagnosis of tuberculous meningitis: An effective and rapid diagnostic method.Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis.TB Summit 2014: prevention, diagnosis, and treatment of tuberculosis-a meeting report of a Euroscicon conference.Degradation of the acyl side chain of the steroid compound cholate in Pseudomonas sp. strain Chol1 proceeds via an aldehyde intermediate.Regulation of the KstR2 regulon of Mycobacterium tuberculosis by a cholesterol catabolite.Tuning the substrate selectivity of meta-cleavage product hydrolase by domain swapping.

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P2860

Characterization of a Carbon-Carbon Hydrolase from Mycobacterium tuberculosis Involved in Cholesterol Metabolism

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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Characterization of a Carbon-C ...... lved in Cholesterol Metabolism

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JBC.M109.058081

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Journal of Biological Chemistry

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Characterization of a carbon-c ...... lved in cholesterol metabolism

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Edward D Lowe

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Katherine C Yam

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Nathan A Lack

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Robin L Owen

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P2860

Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis

Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

Catalysis at the interface: the anatomy of a conformational change in a triglyceride lipase

The tautomeric half-reaction of BphD, a C-C bond hydrolase. Kinetic and structural evidence supporting a key role for histidine 265 of the catalytic triad

The molecular basis for inhibition of BphD, a C-C bond hydrolase involved in polychlorinated biphenyls degradation: large 3-substituents prevent tautomerization

Structure of HsaD, a steroid-degrading hydrolase, fromMycobacterium tuberculosis

A serine protease triad forms the catalytic centre of a triacylglycerol lipase

Coot: model-building tools for molecular graphics

PHENIX: building new software for automated crystallographic structure determination

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scholarly article

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10.1074/JBC.M109.058081

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1

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285

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Lindsay D. Eltis

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2009-10-29T00:00:00Z

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19875455

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Mycobacterium tuberculosis

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2804191

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