Comparison of the structures and peptide binding specificities of the BRCT domains of MDC1 and BRCA1
about
Crystal structure of triple-BRCT-domain of ECT2 and insights into the binding characteristics to CYK-4STRUCTURE-FUNCTION OF THE TUMOR SUPPRESSOR BRCA1BRCT domains: easy as one, two, threePhosphopeptide interactions with BRCA1 BRCT domains: More than just a motifA microchip platform for structural oncology applications.Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint controlImpact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide RecognitionDual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1Saccharomyces cerevisiae Dbf4 Has Unique Fold Necessary for Interaction with Rad53 KinaseMolecular Basis for the Association of Microcephalin (MCPH1) Protein with the Cell Division Cycle Protein 27 (Cdc27) Subunit of the Anaphase-promoting ComplexPeptide library approach to uncover phosphomimetic inhibitors of the BRCA1 C-terminal domainClinically Significant Unclassified Variants in BRCA1 and BRCA2 Genes Among Korean Breast Cancer Patients.The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.Molecular adaptation of telomere associated genes in mammals.Achieving peptide binding specificity and promiscuity by loops: case of the forkhead-associated domain.Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design.Computational and experimental studies of the interaction between phospho-peptides and the C-terminal domain of BRCA1.Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage responseInhibition of BRCT(BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal therapeutic option."DNA Binding Region" of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase CheckpointThe FHA and BRCT domains recognize ADP-ribosylation during DNA damage response.Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks.Molecular Analysis of BRCA1 in Human Breast Cancer Cells Under Oxidative Stress.Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.Discovery of cell-permeable inhibitors that target the BRCT domain of BRCA1 protein by using a small-molecule microarray.Preliminary crystallographic studies of BRCA1 BRCT-ABRAXAS complex.Synthesis of unnatural amino acid derivatives via palladium catalyzed 1,4 addition of boronic acids.ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stabilityStructure-activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1.Reading chromatin signatures after DNA double-strand breaks.Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays.Targeting Phosphopeptide Recognition by the Human BRCA1 Tandem BRCT Domain to Interrupt BRCA1-Dependent Signaling.
P2860
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P2860
Comparison of the structures and peptide binding specificities of the BRCT domains of MDC1 and BRCA1
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@ast
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@en
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@nl
type
label
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@ast
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@en
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@nl
prefLabel
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@ast
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@en
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@nl
P2093
P3181
P1433
P1476
Comparison of the structures a ...... BRCT domains of MDC1 and BRCA1
@en
P2093
J N Mark Glover
Ross A Edwards
Stephen J Campbell
P304
P3181
P356
10.1016/J.STR.2009.12.008
P577
2010-02-10T00:00:00Z