Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
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MIF: Implications in the Pathoetiology of Systemic Lupus ErythematosusThe cross-talk of HIV-1 Tat and methamphetamine in HIV-associated neurocognitive disordersDiversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesA Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF)Structural Interactions Dictate the Kinetics of Macrophage Migration Inhibitory Factor Inhibition by Different Cancer-Preventive IsothiocyanatesDrug Repositioning and Pharmacophore Identification in the Discovery of Hookworm MIF InhibitorsMIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrationsTargeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitmentISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer modelsGlial modulators as potential treatments of psychostimulant abuseAcute neuroimmune modulation attenuates the development of anxiety-like freezing behavior in an animal model of traumatic brain injuryReversal of established traumatic brain injury-induced, anxiety-like behavior in rats after delayed, post-injury neuroimmune suppressionDesign, rationale, and baseline characteristics of the randomized double-blind phase II clinical trial of ibudilast in progressive multiple sclerosisMacrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors.Ibudilast reduces alcohol drinking in multiple animal models of alcohol dependence.Receptor agonists of macrophage migration inhibitory factor.MIF, a controversial cytokine: a review of structural features, challenges, and opportunities for drug development.Development of the Neuroimmune Modulator Ibudilast for the Treatment of Alcoholism: A Randomized, Placebo-Controlled, Human Laboratory Trial.Activation of adult rat CNS endothelial cells by opioid-induced toll-like receptor 4 (TLR4) signaling induces proinflammatory, biochemical, morphological, and behavioral sequelaeCodeine-induced hyperalgesia and allodynia: investigating the role of glial activationIbudilast (AV411), and its AV1013 analog, reduce HIV-1 replication and neuronal death induced by HIV-1 and morphineMacrophage migration inhibitory factor and stearoyl-CoA desaturase 1: potential prognostic markers for soft tissue sarcomas based on bioinformatics analyses.The effects of ibudilast, a glial activation inhibitor, on opioid withdrawal symptoms in opioid-dependent volunteersInhibition of paclitaxel-induced decreases in calcium signaling.Discovering cytokines as targets for chemotherapy-induced painful peripheral neuropathy.Glial cell modulators attenuate methamphetamine self-administration in the rat.Arrest Functions of the MIF Ligand/Receptor Axes in Atherogenesis.Spirohexenolide A targets human macrophage migration inhibitory factor (hMIF)Limiting cardiac ischemic injury by pharmacological augmentation of macrophage migration inhibitory factor-AMP-activated protein kinase signal transduction.Systemic administration of propentofylline, ibudilast, and (+)-naltrexone each reverses mechanical allodynia in a novel rat model of central neuropathic pain.The glial cell modulators, ibudilast and its amino analog, AV1013, attenuate methamphetamine locomotor activity and its sensitization in mice.Ibudilast attenuates subjective effects of methamphetamine in a placebo-controlled inpatient studyCD74: an emerging opportunity as a therapeutic target in cancer and autoimmune disease.Targeting MIF in Cancer: Therapeutic Strategies, Current Developments, and Future Opportunities.Obacunone causes sustained expression of MKP-1 thus inactivating p38 MAPK to suppress pro-inflammatory mediators through intracellular MIF.MIF family cytokines in cardiovascular diseases and prospects for precision-based therapeutics.The phosphodiesterase inhibitor, ibudilast, attenuates neuroinflammation in the MPTP model of Parkinson's disease.Virtual screening and optimization yield low-nanomolar inhibitors of the tautomerase activity of Plasmodium falciparum macrophage migration inhibitory factor.Pathogenic role for macrophage migration inhibitory factor in glioblastoma and its targeting with specific inhibitors as novel tailored therapeutic approach.
P2860
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P2860
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
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2010 nî lūn-bûn
@nan
2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
@nl
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
@ast
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
@en
type
label
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
@nl
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
@ast
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
@en
prefLabel
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast
@nl
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
@ast
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
@en
P2093
P2860
P921
P356
P1476
Allosteric inhibition of macrophage migration inhibitory factor revealed by ibudilast.
@en
P2093
Elias J Lolis
Federico Gaeta
Gregg V Crichlow
Jon J Vermeire
Kirk Johnson
Matt Gross
Michael Cappello
Michael E Hodsdon
P2860
P304
11313-11318
P356
10.1073/PNAS.1002716107
P407
P577
2010-06-08T00:00:00Z