Structure and mechanism of human DNA polymerase η - Test2 - elhamkhani - TriplyDB

Structure and mechanism of human DNA polymerase η

Structure and mechanism of human DNA polymerase η

http://www.wikidata.org/entity/Q27662730

about

Interferon regulatory factor 1 transactivates expression of human DNA polymerase η in response to carcinogen N-methyl-N'-nitro-N-nitrosoguanidine Repriming of DNA synthesis at stalled replication forks by human PrimPol Replication of Structured DNA and its implication in epigenetic stability Mechanism of the nucleotidyl-transfer reaction in DNA polymerase revealed by time-resolved protein crystallography A rescue act: Translesion DNA synthesis past N(2) -deoxyguanosine adducts A new paradigm of DNA synthesis: three-metal-ion catalysis.Mechanism of replication blocking and bypass of Y-family polymerase by bulky acetylaminofluorene DNA adducts Human DNA Polymerase Mutations Allowing Efficient Abasic Site Bypass Replication infidelity via a mismatch with Watson–Crick geometry Role of Human DNA Polymerase κ in Extension Opposite from a cis–syn Thymine Dimer Learning from directed evolution: Thermus aquaticus DNA polymerase mutants with translesion synthesis activity Implications for Damage Recognition during Dpo4-Mediated Mutagenic Bypass of m1G and m3C Lesions Watching DNA polymerase η make a phosphodiester bond Crystal structures and repair studies reveal the identity and the base-pairing properties of the UV-induced spore photoproduct DNA lesion Crystal structures of an archaeal class II DNA photolyase and its complex with UV-damaged duplex DNA Structural insights into the assembly of human translesion polymerase complexes Replication of a carcinogenic nitropyrene DNA lesion by human Y-family DNA polymerase Human DNA Polymerase η Is Pre-Aligned for dNTP Binding and Catalysis A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli Mechanism for priming DNA synthesis by yeast DNA Polymerase α Mechanism of somatic hypermutation at the WA motif by human DNA polymerase η.Structural basis of human DNA polymerase η-mediated chemoresistance to cisplatin.Structural basis for cisplatin DNA damage tolerance by human polymerase η during cancer chemotherapy Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation.Structural Mechanism of Replication Stalling on a Bulky Amino-Polycyclic Aromatic Hydrocarbon DNA Adduct by a Y Family DNA Polymerase Structural Factors That Determine Selectivity of a High Fidelity DNA Polymerase for Deoxy-, Dideoxy-, and Ribonucleotides Sustained active site rigidity during synthesis by human DNA polymerase μ The PAD region in the mycobacterial DinB homologue MsPolIV exhibits positional heterogeneity Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase Structural and mechanistic studies of polymerase bypass of phenanthriplatin DNA damage Capture of a third Mg²⁺ is essential for catalyzing DNA synthesis Mechanisms of Insertion of dCTP and dTTP Opposite the DNA lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η Correlation of phenotype/genotype in a cohort of 23 xeroderma pigmentosum-variant patients reveals 12 new disease-causing POLH mutations Biochemical analysis of DNA polymerase η fidelity in the presence of replication protein A Anti-tumor effects of novel 5-O-acyl plumbagins based on the inhibition of mammalian DNA replicative polymerase activity Steady-state kinetic analysis of DNA polymerase single-nucleotide incorporation products An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η Structure and thermodynamic insights on acetylaminofluorene-modified deletion DNA duplexes as models for frameshift mutagenesis The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site Structural comparison of DNA polymerase architecture suggests a nucleotide gateway to the polymerase active site.

P2860

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P2860

Structure and mechanism of human DNA polymerase η

http://www.wikidata.org/entity/Q27662730

description

2010 nî lūn-bûn

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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2010 թվականի հունիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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Structure and mechanism of human DNA polymerase η

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P2093

Alan R Lehmann

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Chikahide Masutani

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Fumio Hanaoka

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Jae Young Lee

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Mark Gregory

http://www.w3.org/2001/XMLSchema#string

Santiago Ramón-Maiques

http://www.w3.org/2001/XMLSchema#string

Wei Yang

http://www.w3.org/2001/XMLSchema#string

Ye Zhao

http://www.w3.org/2001/XMLSchema#string

Yuji Kondo

http://www.w3.org/2001/XMLSchema#string

P2860

hRAD30 mutations in the variant form of xeroderma pigmentosum

Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex

Molecular analysis of mutations in DNA polymerase eta in xeroderma pigmentosum-variant patients

Mutations in human DNA polymerase eta motif II alter bypass of DNA lesions

Mechanisms of accurate translesion synthesis by human DNA polymerase eta

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

Structure of the catalytic core of S. cerevisiae DNA polymerase eta: implications for translesion DNA synthesis

Crystal structure of a Y-family DNA polymerase in action: a mechanism for error-prone and lesion-bypass replication

Crystal structure of a DNA decamer containing a cis-syn thymine dimer.

Replication of a cis-syn thymine dimer at atomic resolution

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1044-8

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10.1038/NATURE09196

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7301

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465

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Christian Biertümpfel

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44799235

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1019313203

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20577208

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