Structural basis of substrate recognition and specificity in the N-end rule pathway
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The N-end rule pathwayStructure of the HECT C-lobe of the UBR5 E3 ubiquitin ligaseThe UBR-box and its relationship to binuclear RING-like treble clef zinc fingersA platform for functional assessment of large variant libraries in mammalian cells.Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndromeA neurostimulant para-chloroamphetamine inhibits the arginylation branch of the N-end rule pathway.The N-end rule pathway and regulation by proteolysisAlternative ubiquitin activation/conjugation cascades interact with N-end rule ubiquitin ligases to control degradation of RGS proteins.Regulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy.Use of a Conditional Ubr5 Mutant Allele to Investigate the Role of an N-End Rule Ubiquitin-Protein Ligase in Hedgehog Signalling and Embryonic Limb Development.Cardiac Nav 1.5 is modulated by ubiquitin protein ligase E3 component n-recognin UBR3 and 6.Pharmacological Modulation of the N-End Rule Pathway and Its Therapeutic Implications.A d-Amino Acid at the N-Terminus of a Protein Abrogates Its Degradation by the N-End Rule Pathway.Structure of a putative ClpS N-end rule adaptor protein from the malaria pathogen Plasmodium falciparum.Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway.Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.The N-terminal methionine of cellular proteins as a degradation signalp600/UBR4 in the central nervous system.p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis.The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.The ClpS-like N-domain is essential for the functioning of Ubr11, an N-recognin in Schizosaccharomyces pombe.Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays.Crystal structure of the UBR-box from UBR6/FBXO11 reveals domain swapping mediated by zinc binding.The arginylation branch of the N-end rule pathway positively regulates cellular autophagic flux and clearance of proteotoxic proteins.UBL1 of Fusarium verticillioides links the N-end rule pathway to extracellular sensing and plant pathogenesis.A reference-based protein degradation assay without global translation inhibitors.Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development.ZZ-dependent regulation of p62/SQSTM1 in autophagyInsights into degradation mechanism of N-end rule substrates by p62/SQSTM1 autophagy adapter
P2860
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P2860
Structural basis of substrate recognition and specificity in the N-end rule pathway
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Structural basis of substrate recognition and specificity in the N-end rule pathway
@ast
Structural basis of substrate recognition and specificity in the N-end rule pathway
@en
Structural basis of substrate recognition and specificity in the N-end rule pathway
@nl
type
label
Structural basis of substrate recognition and specificity in the N-end rule pathway
@ast
Structural basis of substrate recognition and specificity in the N-end rule pathway
@en
Structural basis of substrate recognition and specificity in the N-end rule pathway
@nl
prefLabel
Structural basis of substrate recognition and specificity in the N-end rule pathway
@ast
Structural basis of substrate recognition and specificity in the N-end rule pathway
@en
Structural basis of substrate recognition and specificity in the N-end rule pathway
@nl
P2860
P3181
P356
P1476
Structural basis of substrate recognition and specificity in the N-end rule pathway
@en
P2093
Edna Matta-Camacho
Flora F Li
P2860
P2888
P304
P3181
P356
10.1038/NSMB.1894
P407
P577
2010-10-01T00:00:00Z
P5875
P6179
1016568224