The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove
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The RNA-binding region of human TRBP interacts with microRNA precursors through two independent domainsAir2p is critical for the assembly and RNA-binding of the TRAMP complex and the KOW domain of Mtr4p is crucial for exosome activationTo edit or not to edit: regulation of ADAR editing specificity and efficiencyTrypanosome RNA editing: the complexity of getting U in and taking U outNew Insights into the Biological Role of Mammalian ADARs; the RNA Editing ProteinsHigh-throughput characterization of protein-RNA interactionsRNA recognition by double-stranded RNA binding domains: a matter of shape and sequenceStructure of a Yeast RNase III dsRBD Complex with a Noncanonical RNA Substrate Provides New Insights into Binding Specificity of dsRBDsSerine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1An extended dsRBD with a novel zinc-binding motif mediates nuclear retention of fission yeast DicerIntrinsic Dynamics of an Extended Hydrophobic Core in the S. cerevisiae RNase III dsRBD Contributes to Recognition of Specific RNA Binding SitesSolution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNAStaufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decaySolution structures of the double-stranded RNA-binding domains from RNA helicase AA bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1Structure and semi-sequence-specific RNA binding of Nrd1Structure of RDE-4 dsRBDs and mutational studies provide insights into dsRNA recognition in the Caenorhabditis elegans RNAi pathwayFunctions of the RNA Editing Enzyme ADAR1 and Their Relevance to Human DiseasesSequence-specific cleavage of dsRNA by Mini-III RNaseMutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signatureInduced folding in RNA recognition by Arabidopsis thaliana DCL1Prediction of a novel RNA binding domain in crocodilepox Zimbabwe Gene 157.Transcript diversification in the nervous system: a to I RNA editing in CNS function and disease developmentMutations underlying Episodic Ataxia type-1 antagonize Kv1.1 RNA editingSubstrate recognition and specificity of double-stranded RNA binding proteins.Structural insight into recognition of phosphorylated threonine-4 of RNA polymerase II C-terminal domain by Rtt103p.'Black sheep' that don't leave the double-stranded RNA-binding domain foldAn RNA electrophoretic mobility shift and mutational analysis of rnp-4f 5'-UTR intron splicing regulatory proteins in Drosophila reveals a novel new role for a dADAR protein isoformA distant cis acting intronic element induces site-selective RNA editing.A novel computational strategy to identify A-to-I RNA editing sites by RNA-Seq data: de novo detection in human spinal cord tissueADAR2 induces reproducible changes in sequence and abundance of mature microRNAs in the mouse brain.The role of human Dicer-dsRBD in processing small regulatory RNAsFinding the target sites of RNA-binding proteins.Regulation of innate immunity through RNA structure and the protein kinase PKR.Predicting sites of ADAR editing in double-stranded RNA.Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2A structural determinant required for RNA editing.Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects.Structural determinants of Arabidopsis thaliana Hyponastic leaves 1 function in vivo.ADAR proteins: double-stranded RNA and Z-DNA binding domains.
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P2860
The Solution Structure of the ADAR2 dsRBM-RNA Complex Reveals a Sequence-Specific Readout of the Minor Groove
description
2010 nî lūn-bûn
@nan
2010 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
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name
The Solution Structure of the ...... ic Readout of the Minor Groove
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The Solution Structure of the ...... ic Readout of the Minor Groove
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The Solution Structure of the ...... ic Readout of the Minor Groove
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The Solution Structure of the ...... ic Readout of the Minor Groove
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The Solution Structure of the ...... ic Readout of the Minor Groove
@en
The Solution Structure of the ...... ic Readout of the Minor Groove
@nl
prefLabel
The Solution Structure of the ...... ic Readout of the Minor Groove
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The Solution Structure of the ...... ic Readout of the Minor Groove
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The Solution Structure of the ...... ic Readout of the Minor Groove
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The Solution Structure of the ...... ic Readout of the Minor Groove
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Christophe Maris
Ctirad Hofr
Florian C Oberstrass
Jennifer L Hood
Lenka Skrisovska
Michal Zimmermann
Muriel Jourdan
Richard Stefl
Ronald B Emeson
P2860
P304
P3181
P356
10.1016/J.CELL.2010.09.026
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P577
2010-10-15T00:00:00Z