Specific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding Domains
about
Engineering RNA-binding proteins with diverse activitiesHigh-throughput characterization of protein-RNA interactionsPatterns and plasticity in RNA-protein interactions enable recruitment of multiple proteins through a single siteAn artificial PPR scaffold for programmable RNA recognitionEvolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA TargetsNop9 binds the central pseudoknot region of 18S rRNAA protein-RNA specificity code enables targeted activation of an endogenous human transcriptA combinatorial amino acid code for RNA recognition by pentatricopeptide repeat proteins.Diversity in genetic in vivo methods for protein-protein interaction studies: from the yeast two-hybrid system to the mammalian split-luciferase system.Nucleic acid recognition by tandem helical repeats.A divergent Pumilio repeat protein family for pre-rRNA processing and mRNA localization.Modular assembly of designer PUF proteins for specific post-transcriptional regulation of endogenous RNAProbing RNA-protein networks: biochemistry meets genomicsTargeted translational regulation using the PUF protein family scaffold.Divergence of Pumilio/fem-3 mRNA binding factor (PUF) protein specificity through variations in an RNA-binding pocketIn vivo analysis of trypanosome mitochondrial RNA function by artificial site-specific RNA endonuclease-mediated knockdown.Human Pumilio proteins recruit multiple deadenylases to efficiently repress messenger RNAsA Nucleolar PUF RNA-binding Protein with Specificity for a Unique RNA Sequence.De-coding and re-coding RNA recognition by PUF and PPR repeat proteins.Biochemical characterization of the Caenorhabditis elegans FBF.CPB-1 translational regulation complex identifies conserved protein interaction hotspots.Engineered proteins with Pumilio/fem-3 mRNA binding factor scaffold to manipulate RNA metabolism.How a CCA sequence protects mature tRNAs and tRNA precursors from action of the processing enzyme RNase BN/RNase ZPentatricopeptide repeats: modular blocks for building RNA-binding proteins.Treatment of type 1 myotonic dystrophy by engineering site-specific RNA endonucleases that target (CUG)(n) repeats.Modular recognition of nucleic acids by PUF, TALE and PPR proteins.Engineering RNA-binding proteins for biologyProtein universe containing a PUA RNA-binding domain.Engineering reprogrammable RNA-binding proteins for study and manipulation of the transcriptome.A pumilio homolog in Polycelis sp.Engineering RNA endonucleases with customized sequence specificities.Inducible Control of mRNA Transport Using Reprogrammable RNA-Binding Proteins.The dataset for protein-RNA binding affinity.Engineering specificity changes on a RanBP2 zinc finger that binds single-stranded RNA.Evolutionarily dynamic roles of a PUF RNA-binding protein in the somatic development of Caenorhabditis briggsae.Structural basis for the specific recognition of 18S rRNA by APUM23.An Arabidopsis divergent pumilio protein, APUM24, is essential for embryogenesis and required for faithful pre-rRNA processing.A Genetically Encodable System for Sequence-Specific Detection of RNAs in Two Colors.Tetramolecular fluorescence complementation for detection of specific RNAs in vitro.Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells.Bidirectional regulation of mRNA translation in mammalian cells by using PUF domains.
P2860
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P2860
Specific and Modular Binding Code for Cytosine Recognition in Pumilio/FBF (PUF) RNA-binding Domains
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@ast
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@en
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@nl
type
label
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@ast
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@en
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@nl
prefLabel
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@ast
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@en
Specific and Modular Binding C ...... /FBF (PUF) RNA-binding Domains
@nl
P2093
P2860
P356
P1476
Specific and modular binding c ...... /FBF (PUF) RNA-binding domains
@en
P2093
Caleb Cassidy-Amstutz
Chunhua Li
Mark R Jezyk
Rebecca Bigler
Zefeng Wang
P2860
P304
26732-26742
P356
10.1074/JBC.M111.244889
P407
P577
2011-06-08T00:00:00Z