Structural Basis of Regiospecificity of a Mononuclear Iron Enzyme in Antibiotic Fosfomycin Biosynthesis
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Complexity generation during natural product biosynthesis using redox enzymesMechanistic studies of an unprecedented enzyme-catalysed 1,2-phosphono-migration reactionEvidence that the fosfomycin-producing epoxidase, HppE, is a non-heme-iron peroxidaseEnzymatic chemistry of cyclopropane, epoxide, and aziridine biosynthesis.Assembly of the unusual oxacycles in the orthosomycin antibiotics.Mechanistic investigation of methylphosphonate synthase, a non-heme iron-dependent oxygenase.Evidence for radical-mediated catalysis by HppE: a study using cyclopropyl and methylenecyclopropyl substrate analoguesReaction of HppE with substrate analogues: evidence for carbon-phosphorus bond cleavage by a carbocation rearrangement.Characterization of Two Late-Stage Enzymes Involved in Fosfomycin Biosynthesis in Pseudomonads.Beyond ferryl-mediated hydroxylation: 40 years of the rebound mechanism and C-H activation.Mechanistic consequences of chiral radical clock probes: analysis of the mononuclear non-heme iron enzyme HppE with 2-hydroxy-3-methylenecyclopropyl radical clock substrates.Dioxygen activation by nonheme iron enzymes with the 2-His-1-carboxylate facial triad that generate high-valent oxoiron oxidants.Bacillus anthracis Prolyl 4-Hydroxylase Interacts with and Modifies Elongation Factor Tu.On the catalytic mechanism of (S)-2-hydroxypropylphosphonic acid epoxidase (HppE): a hybrid DFT study.
P2860
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P2860
Structural Basis of Regiospecificity of a Mononuclear Iron Enzyme in Antibiotic Fosfomycin Biosynthesis
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@ast
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@en
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@nl
type
label
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@ast
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@en
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@nl
prefLabel
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@ast
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@en
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@nl
P2093
P2860
P356
P1476
Structural Basis of Regiospeci ...... biotic Fosfomycin Biosynthesis
@en
P2093
Catherine L Drennan
Hung-wen Liu
Luke J Higgins
Mishtu Dey
P2860
P304
P356
10.1021/JA2025728
P407
P577
2011-07-27T00:00:00Z