Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
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Crystal Structure of the Acyltransferase Domain of the Iterative Polyketide Synthase in Enediyne BiosynthesisA Close Look at a Ketosynthase from a Trans-Acyltransferase Modular Polyketide SynthaseStructural and functional studies of atrans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective α- and β-ketoreductionArchitecture of the polyketide synthase module: surprises from electron cryo-microscopyBiochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide BiosynthesisSolving the Puzzle of One-Carbon Loss in Ripostatin Biosynthesis.Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways.Use of transmission electron microscopy to identify nanocrystals of challenging protein targetsComparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.Evaluating nonpolar surface area and liquid chromatography/mass spectrometry response: an application for site occupancy measurements for enzyme intermediates in polyketide biosynthesis.A polyketide synthase acyltransferase domain structure suggests a recognition mechanism for its hydroxymalonyl-acyl carrier protein substrate.Genetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering.Polyketide proofreading by an acyltransferase-like enzyme.Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering.The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex.Harnessing natural product assembly lines: structure, promiscuity, and engineering.Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.Structural analysis of protein-protein interactions in type I polyketide synthasesEngineering the acyltransferase substrate specificity of assembly line polyketide synthases.The structures of type I polyketide synthases.The structural role of the carrier protein--active controller or passive carrier.Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases.Uncovering the structures of modular polyketide synthases.The structural biology of biosynthetic megaenzymes.Biosynthesis of polyketides by trans-AT polyketide synthases.A Protein Interaction Map of the Kalimantacin Biosynthesis Assembly LineStructure and mechanism of assembly line polyketide synthases.Reprogramming acyl carrier protein interactions of an Acyl-CoA promiscuous trans-acyltransferase.Elucidating the mechanism of fluorinated extender unit loading for improved production of fluorine-containing polyketides.Biosynthesis of the antifungal haterumalide, oocydin A, in Serratia, and its regulation by quorum sensing, RpoS and Hfq.A photocrosslinking assay for reporting protein interactions in polyketide and fatty acid synthases.Genetic Mapping and Biochemical Basis of Yellow Feather Pigmentation in Budgerigars.The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.Acyl hydrolases from trans-AT polyketide synthases target acetyl units on acyl carrier proteins.Substrate Specificity of Acyltransferase Domains for Efficient Transfer of Acyl Groups
P2860
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P2860
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@ast
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@en
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@nl
type
label
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@ast
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@en
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@nl
prefLabel
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@ast
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@en
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase
@en
P2093
Chaitan Khosla
David E Cane
Fong T Wong
Irimpan I Mathews
P2860
P304
P3181
P356
10.1021/BI200632J
P407
P577
2011-08-02T00:00:00Z