Tapping natural reservoirs of homing endonucleases for targeted gene modification
about
Optimising homing endonuclease gene drive performance in a semi-refractory species: the Drosophila melanogaster experienceTargeted gene disruption to cure HIVHoming endonucleases: DNA scissors on a missionExpanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence spaceVisualizing phosphodiester-bond hydrolysis by an endonucleaseProtein sequence alignment analysis by local covariation: coevolution statistics detect benchmark alignment errors.LAHEDES: the LAGLIDADG homing endonuclease database and engineering servermegaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX)Control of catalytic efficiency by a coevolving network of catalytic and noncatalytic residues.The I-TevI nuclease and linker domains contribute to the specificity of monomeric TALENsMassively parallel determination and modeling of endonuclease substrate specificityThe developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vectorThe design and in vivo evaluation of engineered I-OnuI-based enzymes for HEG gene driveFunctional genetics for all: engineered nucleases, CRISPR and the gene editing revolutionHoming endonucleases: from genetic anomalies to programmable genomic clippersA tetO Toolkit To Alter Expression of Genes in Saccharomyces cerevisiae.Generation and Inheritance of Targeted Mutations in Potato (Solanum tuberosum L.) Using the CRISPR/Cas SystemUsing Group II Introns for Attenuating the In Vitro and In Vivo Expression of a Homing EndonucleaseMonomeric site-specific nucleases for genome editing.Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.Accelerated genome engineering through multiplexing.The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.Perpetuating the homing endonuclease life cycle: identification of mutations that modulate and change I-TevI cleavage preferenceRapid assembly of customized TALENs into multiple delivery systems.Biasing genome-editing events toward precise length deletions with an RNA-guided TevCas9 dual nuclease.Reprogramming homing endonuclease specificity through computational design and directed evolution.Programmable Genome Editing Tools and their Regulation for Efficient Genome Engineering.The Development of TALE Nucleases for Biotechnology.Redesign of extensive protein-DNA interfaces of meganucleases using iterative cycles of in vitro compartmentalization.Molecular scissors for in situ cellular repair.Targeted gene therapies: tools, applications, optimizationRecent advances in targeted genome engineering in mammalian systems.Salient Features of Endonuclease Platforms for Therapeutic Genome EditingGene editing for cell engineering: trends and applications.Genome Editing Techniques and Their Therapeutic Applications.The nontoxic cell cycle modulator indirubin augments transduction of adeno-associated viral vectors and zinc-finger nuclease-mediated gene targeting.Germline excision of transgenes in Aedes aegypti by homing endonucleases.Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses.Engineering of customized meganucleases via in vitro compartmentalization and in cellulo optimization.
P2860
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P2860
Tapping natural reservoirs of homing endonucleases for targeted gene modification
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@ast
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@en
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@nl
type
label
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@ast
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@en
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@nl
prefLabel
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@ast
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@en
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@nl
P2093
P2860
P3181
P356
P1476
Tapping natural reservoirs of homing endonucleases for targeted gene modification
@en
P2093
Abigail R Lambert
Amanda Nga-Sze Mak
Andrew M Scharenberg
Barry L Stoddard
David R Edgell
Kyle Jacoby
Russell J Dickson
Ryo Takeuchi
P2860
P304
13077-13082
P3181
P356
10.1073/PNAS.1107719108
P407
P577
2011-07-22T00:00:00Z