Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels
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Zinc as Allosteric Ion Channel Modulator: Ionotropic Receptors as MetalloproteinsCanine CNGA3 Gene Mutations Provide Novel Insights into Human Achromatopsia-Associated Channelopathies and TreatmentGating of the designed trimeric/tetrameric voltage-gated H+channelSpeed, sensitivity, and stability of the light response in rod and cone photoreceptors: facts and modelsWhole exome analysis identifies frequent CNGA1 mutations in Japanese population with autosomal recessive retinitis pigmentosaA large animal model for CNGB1 autosomal recessive retinitis pigmentosa.A cyclic nucleotide-gated channel mutation associated with canine daylight blindness provides insight into a role for the S2 segment tri-Asp motif in channel biogenesis.cGMP in mouse rods: the spatiotemporal dynamics underlying single photon responses.Conformational rearrangements in the transmembrane domain of CNGA1 channels revealed by single-molecule force spectroscopy.A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.Endoplasmic reticulum stress-associated cone photoreceptor degeneration in cyclic nucleotide-gated channel deficiency.Achromatopsia caused by novel missense mutations in the CNGA3 gene.Homozygous missense variant in the human CNGA3 channel causes cone-rod dystrophyAAV-Mediated Gene Supplementation Therapy in Achromatopsia Type 2: Preclinical Data on Therapeutic Time Window and Long-Term EffectsTwo structural components in CNGA3 support regulation of cone CNG channels by phosphoinositides.The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural FlexibilityCNGA3 achromatopsia-associated mutation potentiates the phosphoinositide sensitivity of cone photoreceptor CNG channels by altering intersubunit interactionsLoss of cone cyclic nucleotide-gated channel leads to alterations in light response modulating system and cellular stress response pathways: a gene expression profiling study.Cell- and subunit-specific mechanisms of CNG channel ciliary trafficking and localization in C. elegans.Molecular mechanism of TRP channelsGene replacement therapy for retinal CNG channelopathies.Gene therapy for achromatopsia.Deciphering the function of the CNGB1b subunit in olfactory CNG channels.Detecting stoichiometry of macromolecular complexes in live cells using FRET.Identification of major zinc-binding proteins from a marine cyanobacterium: insight into metal uptake in oligotrophic environments.Why are rods more sensitive than cones?Patients and animal models of CNGβ1-deficient retinitis pigmentosa support gene augmentation approach.Overexpression and Purification of Human Cis-prenyltransferase in Escherichia coli.Structural and evolutionary versatility in protein complexes with uneven stoichiometry.Structural insights into the mechanisms of CNBD channel function.Retinal Cyclic Nucleotide-Gated Channels: From Pathophysiology to Therapy.
P2860
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P2860
Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@ast
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@en
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@nl
type
label
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@ast
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@en
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@nl
prefLabel
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@ast
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@en
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@nl
P2093
P2860
P3181
P356
P1476
Molecular mechanism for 3:1 su ...... nucleotide-gated ion channels
@en
P2093
Kevin D Black
Noah G Shuart
Stacey S Camp
William N Zagotta
P2860
P2888
P3181
P356
10.1038/NCOMMS1466
P407
P50
P577
2011-08-30T00:00:00Z
P5875
P6179
1040942542