HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
about
Human leukocyte Antigen-DM polymorphisms in autoimmune diseasesA step-by-step overview of the dynamic process of epitope selection by major histocompatibility complex class II for presentation to helper T cellsMHC and Evolution in TeleostsSusceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with PeptideThe binding of TAPBPR and Tapasin to MHC class I is mutually exclusive.Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates.Pathways of antigen processing.Differences in meiotic recombination rates in childhood acute lymphoblastic leukemia at an MHC class II hotspot close to disease associated haplotypes.An unstable Th epitope of P. falciparum fosters central memory T cells and anti-CS antibody responses.The MHC class II cofactor HLA-DM interacts with Ig in B cells.HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation.Elevation of c-MYC disrupts HLA class II-mediated immune recognition of human B cell tumorsNatural polymorphisms in Tap2 influence negative selection and CD4∶CD8 lineage commitment in the ratEvaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions.The Thermodynamic Mechanism of Peptide-MHC Class II Complex Formation Is a Determinant of Susceptibility to HLA-DM.pH-susceptibility of HLA-DO tunes DO/DM ratios to regulate HLA-DM catalytic activity.Ubiquitination of HLA-DO by MARCH family E3 ligases.CD4 T cell epitope specificity determines follicular versus non-follicular helper differentiation in the polyclonal response to influenza infection or vaccinationContribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis.Thermodynamics of Peptide-MHC Class II Interactions: Not all Complexes are Created Equal.Mechanisms of peptide repertoire selection by HLA-DMMonitoring the immune response to vaccination with an inactivated vaccine associated to bovine neonatal pancytopenia by deep sequencing transcriptome analysis in cattle.HLA-DO and Its Role in MHC Class II Antigen Presentation.Structural Characteristics of HLA-DQ that May Impact DM Editing and Susceptibility to Type-1 Diabetes.HLA-DM Focuses on Conformational Flexibility Around P1 Pocket to Catalyze Peptide Exchange.Higher throughput methods of identifying T cell epitopes for studying outcomes of altered antigen processing and presentationToward a Network Model of MHC Class II-Restricted Antigen Processing.Inhibition of HLA-DM Mediated MHC Class II Peptide Loading by HLA-DO Promotes Self ToleranceHLA-DM and HLA-DO, key regulators of MHC-II processing and presentation.Measurement of Peptide Binding to MHC Class II Molecules by Fluorescence Polarization.Determinants of immunodominance for CD4 T cells.Present Yourself! By MHC Class I and MHC Class II Molecules.Major Histocompatibility Complex (MHC) Class I and MHC Class II Proteins: Conformational Plasticity in Antigen Presentation.The Other Function: Class II-Restricted Antigen Presentation by B Cells.Introduction: MHC/KIR and governance of specificity.A novel method to measure HLA-DM-susceptibility of peptides bound to MHC class II molecules based on peptide binding competition assay and differential IC(50) determination.Neutralizing Antibody Responses to Viral Infections Are Linked to the Non-classical MHC Class II Gene H2-Ob.MHC class II complexes sample intermediate states along the peptide exchange pathway.Identification of the major histocompatibility complex class-II DM and DO alleles in a cohort of northern pig-tailed macaques (Macaca leonina).Transcription profile analysis of the endometrium revealed molecular markers of the personalized 'window of implantation' during in vitro fertilization.
P2860
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P2860
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@ast
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@en
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@nl
type
label
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@ast
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@en
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@nl
prefLabel
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@ast
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@en
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@nl
P2093
P2860
P3181
P356
P1476
HLA-DO acts as a substrate mimic to inhibit HLA-DM by a competitive mechanism
@en
P2093
Abigail I Guce
Corrie A Painter
Elizabeth D Mellins
Lawrence J Stern
Sarah E Mortimer
Taejin Yoon
P2860
P2888
P3181
P356
10.1038/NSMB.2460
P577
2013-01-01T00:00:00Z
P5875
P6179
1017924374