Neutron and X-ray Crystal Structures of a Perdeuterated Enzyme Inhibitor Complex Reveal the Catalytic Proton Network of the Toho-1 -Lactamase for the Acylation Reaction
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XModeScore: a novel method for accurate protonation/tautomer-state determination using quantum-mechanically driven macromolecular X-ray crystallographic refinement.Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.Long-Range Electrostatics-Induced Two-Proton Transfer Captured by Neutron Crystallography in an Enzyme Catalytic Site.Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam SubstrateThe structure of Toho1 β-lactamase in complex with penicillin reveals the role of Tyr105 in substrate recognition.Seeing the chemistry in biology with neutron crystallography.One ring to rule them all: Current trends in combating bacterial resistance to the β-lactamsBiochemistry. Fishing for peroxidase protons.Mechanisms of proton relay and product release by Class A β-lactamase at ultrahigh resolution.Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into Antigen 85 catalysis.On the structure of water and chloride ion interactions with a peptide backbone in solutionThe rise of neutron cryo-crystallographyCryogenic neutron protein crystallography: routine methods and potential benefits
P2860
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P2860
Neutron and X-ray Crystal Structures of a Perdeuterated Enzyme Inhibitor Complex Reveal the Catalytic Proton Network of the Toho-1 -Lactamase for the Acylation Reaction
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2013 nî lūn-bûn
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2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2013 թվականի փետրվարին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
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Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
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Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
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Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
@ast
Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
@en
Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
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Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
@ast
Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
@en
Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
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P2093
P2860
P50
P921
P356
P1476
Neutron and X-ray Crystal Stru ...... ase for the Acylation Reaction
@en
P2093
Joseph D Ng
Kevin L Weiss
Stephen J Tomanicek
P2860
P304
P356
10.1074/JBC.M112.436238
P407
P577
2013-02-15T00:00:00Z