Pyridine-Substituted Desoxyritonavir Is a More Potent Inhibitor of Cytochrome P450 3A4 than Ritonavir
about
Ritonavir analogues as a probe for deciphering the cytochrome P450 3A4 inhibitory mechanismCurrent Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsStructure-Based Inhibitor Design for Evaluation of a CYP3A4 Pharmacophore Model.Structural basis for regiospecific midazolam oxidation by human cytochrome P450 3A4.Membrane Fluidity Modulates Thermal Stability and Ligand Binding of Cytochrome P4503A4 in Lipid Nanodiscs.Intersection of the Roles of Cytochrome P450 Enzymes with Xenobiotic and Endogenous Substrates: Relevance to Toxicity and Drug Interactions.The Cytochrome P450 3A4 Has Three Major Conformations: New Clues to Drug Recognition by this Promiscuous Enzyme.Spectroscopic studies of the cytochrome P450 reaction mechanisms.Inhibition of Human CYP3A4 by Rationally Designed Ritonavir-Like Compounds: Impact and Interplay of the Side Group Functionalities.The X-Ray Crystal Structure of the Human Mono-Oxygenase Cytochrome P450 3A5-Ritonavir Complex Reveals Active Site Differences between P450s 3A4 and 3A5.Structure and Dynamics of Human Drug-Metabolizing Cytochrome P450 Enzymes
P2860
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P2860
Pyridine-Substituted Desoxyritonavir Is a More Potent Inhibitor of Cytochrome P450 3A4 than Ritonavir
description
2013 nî lūn-bûn
@nan
2013 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@ast
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@en
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@nl
type
label
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@ast
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@en
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@nl
prefLabel
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@ast
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@en
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@nl
P2860
P356
P1476
Pyridine-Substituted Desoxyrit ...... chrome P450 3A4 than Ritonavir
@en
P2093
Irina F Sevrioukova
Thomas L Poulos
P2860
P304
P356
10.1021/JM400288Z
P407
P577
2013-05-09T00:00:00Z