Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains
about
Crystal Structure of Firefly Luciferase in a Second Catalytic Conformation Supports a Domain Alternation MechanismStructure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesisTwo Structures of a Thiazolinyl Imine Reductase from Yersinia enterocolitica Provide Insight into Catalysis and Binding to the Nonribosomal Peptide Synthetase Module of HMWP1Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating EnzymesStructure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein DomainsCrystal structures of the first condensation domain of CDA synthetase suggest conformational changes during the synthetic cycle of nonribosomal peptide synthetases.Structure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetryAntimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide SynthetasesStructure of the epimerization domain of tyrocidine synthetase AThe structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenaseThe crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteinsHigh-resolution structures of the D-alanyl carrier protein (Dcp) DltC from Bacillus subtilis reveal equivalent conformations of apo- and holo-formsStructures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-Like Proteins Support a Highly Dynamic Domain ArchitectureNew Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide SynthesisCharacterization of cereulide synthetase, a toxin-producing macromolecular machineBisubstrate Inhibitors of Biotin Protein Ligase in Mycobacterium tuberculosis Resistant to Cyclonucleoside Formation.Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases.Engineering polyketide synthases and nonribosomal peptide synthetases.The structure of S. lividans acetoacetyl-CoA synthetase shows a novel interaction between the C-terminal extension and the N-terminal domainBreaking a pathogen's iron will: Inhibiting siderophore production as an antimicrobial strategyFunctional profiling of adenylation domains in nonribosomal peptide synthetases by competitive activity-based protein profiling.Production of the Ramoplanin Activity Analogue by Double Gene InactivationDesigned Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosaSNaPe: a versatile method to generate multiplexed protein fusions using synthetic linker peptides for in vitro applications.Solution Structure of a Nonribosomal Peptide Synthetase Carrier Protein Loaded with Its Substrate Reveals Transient, Well-Defined ContactsStructural basis for specificity and promiscuity in a carrier protein/enzyme system from the sulfur cycle.Harnessing natural product assembly lines: structure, promiscuity, and engineering.Structural Biology of Nonribosomal Peptide SynthetasesStructure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.Structures of two distinct conformations of holo-non-ribosomal peptide synthetasesEngineering the substrate specificity of the DhbE adenylation domain by yeast cell surface display.Biochemical characterization and structural insight into aliphatic β-amino acid adenylation enzymes IdnL1 and CmiS6.Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis.The structural biology of biosynthetic megaenzymes.A structural model for multimodular NRPS assembly lines.Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity.Biosynthetic engineering of nonribosomal peptide synthetases.Structural insight into the necessary conformational changes of modular nonribosomal peptide synthetases.Nonribosomal peptide synthetase biosynthetic clusters of ESKAPE pathogens.Prediction of the substrate for nonribosomal peptide synthetase (NRPS) adenylation domains by virtual screening.
P2860
Q27671045-7A7EE8D9-E378-4641-A98F-B224CC185052Q27674337-B58F05FA-81E1-4533-939A-CB9E82DD168BQ27674548-EF90E7F7-F27B-4D8E-BC51-32F0FAFD1FD4Q27675322-80E80073-FC94-46B0-8100-3609BA148593Q27678231-6BCF4F67-F0BE-498C-9BAA-B7C5D93C5718Q27678575-02C80822-7D75-4AFC-800D-031CEB4B9FDAQ27679256-B8130DEB-209C-40C3-9449-7C585F2F7FB3Q27684837-CA70E4E2-D808-4BF6-9EC8-4F9579C35E48Q27690209-20DC6DC1-3E66-4E3B-A044-96A13C67CD7CQ27694596-57EDAA73-F623-45B3-A016-E3E58E62890DQ27694605-C743DEA1-A21F-42EA-89F5-FBC2CF149688Q27701584-E55F74E1-0F17-41DA-AC79-BF7CFD5A976BQ27728008-0A1C000F-862C-4A08-B8D9-727CDD5F2694Q28075494-0AFB56F1-227B-43F4-B1C6-B19424EFBC1BQ28547825-1B5B9C12-DC0F-46A1-9A73-2600ACC3A7CEQ29346756-F468B918-1412-46D5-882A-AD4CF3FD308BQ34254489-B1A23934-544A-496A-B566-79D7E3FE1A27Q34739957-749FC3D2-7C6D-4A35-BDDD-906417ED597DQ35085276-EA1284DE-FFD1-4D06-9116-A8444E8B398CQ35688927-02562EFD-CE7C-4D25-8862-E586A5C5191FQ35771974-264CD058-C632-4960-A420-064DC113C482Q36009762-68C2DCFB-004C-4B13-8850-CBCF5953B971Q36141081-B8B8D70A-9799-4502-9973-829EFBDE66E6Q36210973-B7D144CA-4443-4BE7-BA39-750439A18ACAQ36398859-1D21C730-945F-447E-BC11-9DFB7ED94D9CQ36435139-4A2FB2FD-577C-4D61-8259-40062A3681E1Q36578763-57E79760-77EA-4DC4-8A5B-37B578E79E6AQ36597567-60B9B374-9D19-41DD-8AC7-4F42FEE90F65Q36607621-6B5F31D2-9ED0-4140-B8B0-40E868A8D6DBQ36830735-7D87E6A7-CE50-447F-A89A-36E0A6B901B0Q37253864-6FFBE682-0AB7-484D-977E-B3818FF8755FQ38288656-607C0846-EBF7-4DAC-B376-FEF116D44A8DQ38333136-CAFC802B-9A97-4CF8-A57C-E381C9BD7D33Q38568948-5B046E2C-42F1-4692-8705-FBF0D3DAB339Q38597513-BAB704D6-96DD-462A-8888-8634822F6D0DQ38680826-96F37E7A-700F-4312-9E78-186C56EA091EQ38837173-151D2545-C432-453E-81C9-193F3899ABA9Q38965803-6151F7FF-DBB9-4FDE-AB30-90DBC9870AD4Q39392982-15E926E7-B653-40EE-8EA0-4DAD7E363A4BQ40551036-9065A257-2813-4076-87A4-8F02A068984B
P2860
Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural and Functional Inve ...... on and Carrier Protein Domains
@ast
Structural and Functional Inve ...... on and Carrier Protein Domains
@en
Structural and Functional Inve ...... on and Carrier Protein Domains
@nl
type
label
Structural and Functional Inve ...... on and Carrier Protein Domains
@ast
Structural and Functional Inve ...... on and Carrier Protein Domains
@en
Structural and Functional Inve ...... on and Carrier Protein Domains
@nl
prefLabel
Structural and Functional Inve ...... on and Carrier Protein Domains
@ast
Structural and Functional Inve ...... on and Carrier Protein Domains
@en
Structural and Functional Inve ...... on and Carrier Protein Domains
@nl
P2093
P2860
P3181
P1476
Structural and functional inve ...... on and carrier protein domains
@en
P2093
Courtney C Aldrich
Daniel J Wilson
Jesse A Sundlov
P2860
P304
P3181
P356
10.1016/J.CHEMBIOL.2011.11.013
P577
2012-02-01T00:00:00Z