The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
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Epithelial mesenchymal transition from a natural gestational orchestration to a bizarre cancer disturbanceα-Catenin-mediated cadherin clustering couples cadherin and actin dynamics.Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturationDimer asymmetry defines α-catenin interactionsAn Autoinhibited Structure of -Catenin and Its Implications for Vinculin Recruitment to Adherens JunctionsStructural and Thermodynamic Characterization of Cadherin{middle dot} -Catenin{middle dot} -Catenin Complex FormationLocal VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers.E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretchαE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factorsPresynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels.The evolutionary origin of epithelial cell-cell adhesion mechanismsLipid binding promotes oligomerization and focal adhesion activity of vinculinStructural Determinants of the Mechanical Stability of α-Catenin.The mechanotransduction machinery at work at adherens junctions.α-Catenin and vinculin cooperate to promote high E-cadherin-based adhesion strengthSpecific conserved C-terminal amino acids of Caenorhabditis elegans HMP-1/α-catenin modulate F-actin binding independently of vinculin.α-catenin, vinculin, and F-actin in strengthening E-cadherin cell-cell adhesions and mechanosensing.Characterization of the Cadherin-Catenin Complex of the Sea Anemone Nematostella vectensis and Implications for the Evolution of Metazoan Cell-Cell AdhesionThe adherens junction: a mosaic of cadherin and nectin clusters bundled by actin filaments.Vinculin and Rab5 complex is required [correction of requited]for uptake of Staphylococcus aureus and interleukin-6 expressionVinculin, cadherin mechanotransduction and homeostasis of cell-cell junctions.Cadherin mechanotransduction in tissue remodeling.Mechanical control of the endothelial barrier.Force-induced remodelling of proteins and their complexesCell adhesion in epidermal development and barrier formation.Structural and functional characterization of the α-catenin·β-catenin binding interface in Caenorhabditis elegans reveals conserved requirements for cell-cell adhesion in metazoans.Cadherin-mediated cell-cell interactions in normal and cancer cells.Cell-cell junctional mechanotransduction in endothelial remodeling.Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.Zygotic vinculin is not essential for embryonic development in zebrafish.Biophysical Tools to Study Cellular Mechanotransduction.Monomeric α-catenin links cadherin to the actin cytoskeleton.Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force.Salt bridges gate α-catenin activation at intercellular junctions.Nonmuscle myosin IIA is involved in recruitment of apical junction components through activation of α-catenin.
P2860
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P2860
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
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2012 nî lūn-bûn
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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2012 թվականի մայիսին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年論文
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2012年论文
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name
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@ast
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@en
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@nl
type
label
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@ast
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@en
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@nl
prefLabel
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@ast
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@en
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@nl
P2860
P3181
P356
P1476
The Cytoskeletal Protein -Catenin Unfurls upon Binding to Vinculin
@en
P2093
Erumbi S Rangarajan
P2860
P304
P3181
P356
10.1074/JBC.M112.351023
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P50
P577
2012-05-25T00:00:00Z