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Eukaryote-specific insertion elements control human ARGONAUTE slicer activityDuplication and Diversification of Dipteran Argonaute Genes, and the Evolutionary Divergence of Piwi and AubergineAnatomy of RISC: how do small RNAs and chaperones activate Argonaute proteins?Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virusEvolutionary conservation and expression of human RNA-binding proteins and their role in human genetic diseaseA prokaryotic twist on argonaute functionA Dynamic Search Process Underlies MicroRNA Targeting.Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid GuidesMechanistic Insights into Archaeal and Human Argonaute Substrate Binding and Cleavage PropertiesSlicer-independent mechanism drives small-RNA strand separation during human RISC assemblysiRNA carrying an (E)-vinylphosphonate moiety at the 5΄ end of the guide strand augments gene silencing by enhanced binding to human Argonaute-2.Inferring the evolutionary history of primate microRNA binding sites: overcoming motif counting biasesGeneration of catalytic human Ago4 identifies structural elements important for RNA cleavageMicroRNA-directed cleavage of targets: mechanism and experimental approaches.ARGONAUTE PIWI domain and microRNA duplex structure regulate small RNA sorting in Arabidopsis.Structural basis for microRNA targetingThe evolutionary journey of Argonaute proteinsFrom guide to target: molecular insights into eukaryotic RNA-interference machinery.Markov State Models Reveal a Two-Step Mechanism of miRNA Loading into the Human Argonaute Protein: Selective Binding followed by Structural Re-arrangement.Biochemical isolation of Argonaute protein complexes by Ago-APPAssembly and analysis of eukaryotic Argonaute-RNA complexes in microRNA-target recognition.The evolution of microRNA pathway protein components in CnidariaFrom early lessons to new frontiers: the worm as a treasure trove of small RNA biologyConformational Dynamics of Ago-Mediated Silencing ProcessesPhosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing in vivo.Conservation of miRNA-mediated silencing mechanisms across 600 million years of animal evolution.Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels.Novel Insights into Guide RNA 5'-Nucleoside/Tide Binding by Human Argonaute 2.Structural Analysis of Human Argonaute-2 Bound to a Modified siRNA Guide.Structural basis for the recognition of guide RNA and target DNA heteroduplex by Argonaute.Water-mediated recognition of t1-adenosine anchors Argonaute2 to microRNA targets.Cloning and Identification of Recombinant Argonaute-Bound Small RNAs Using Next-Generation Sequencing.Peptide-Based Isolation of Argonaute Protein Complexes Using Ago-APP.Human Argonaute3 has slicer activity.Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs.Reconstitution of RNA Interference Machinery.Nucleic Acid-Binding Assay of Argonaute Protein Using Fluorescence Polarization.Helix-7 in Argonaute2 shapes the microRNA seed region for rapid target recognition.Multivalent Recruitment of Human Argonaute by GW182.Structural Foundations of RNA Silencing by Argonaute.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
The Making of a Slicer: Activation of Human Argonaute-1
@ast
The Making of a Slicer: Activation of Human Argonaute-1
@en
The Making of a Slicer: Activation of Human Argonaute-1
@nl
type
label
The Making of a Slicer: Activation of Human Argonaute-1
@ast
The Making of a Slicer: Activation of Human Argonaute-1
@en
The Making of a Slicer: Activation of Human Argonaute-1
@nl
prefLabel
The Making of a Slicer: Activation of Human Argonaute-1
@ast
The Making of a Slicer: Activation of Human Argonaute-1
@en
The Making of a Slicer: Activation of Human Argonaute-1
@nl
P2093
P2860
P3181
P1433
P1476
The Making of a Slicer: Activation of Human Argonaute-1
@en
P2093
Astrid D Haase
Christopher R Faehnle
Elad Elkayam
P2860
P304
P3181
P356
10.1016/J.CELREP.2013.05.033
P577
2013-06-27T00:00:00Z