The initiation of mammalian protein synthesis and mRNA scanning mechanism - Test2 - elhamkhani - TriplyDB

The initiation of mammalian protein synthesis and mRNA scanning mechanism

The initiation of mammalian protein synthesis and mRNA scanning mechanism

http://www.wikidata.org/entity/Q27679159

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An RNA trapping mechanism in Alphavirus mRNA promotes ribosome stalling and translation initiation Eukaryote-specific extensions in ribosomal proteins of the small subunit: Structure and function Why is start codon selection so precise in eukaryotes?Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA Structure of a yeast 40S-eIF1-eIF1A-eIF3-eIF3j initiation complex Quantitative studies of mRNA recruitment to the eukaryotic ribosome Cryo-EM study of start codon selection during archaeal translation initiation Re-analysis of cryoEM data on HCV IRES bound to 40S subunit of human ribosome integrated with recent structural information suggests new contact regions between ribosomal proteins and HCV RNA Systematic genomic and translational efficiency studies of uveal melanoma.Rps5-Rps16 communication is essential for efficient translation initiation in yeast S. cerevisiae.Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complex Structural changes enable start codon recognition by the eukaryotic translation initiation complex.Human eukaryotic initiation factor 2 (eIF2)-GTP-Met-tRNAi ternary complex and eIF3 stabilize the 43 S preinitiation complex.eIF5 and eIF5B together stimulate 48S initiation complex formation during ribosomal scanning.Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor β1-3 (TGF-β1-3).Conformational changes in the P site and mRNA entry channel evoked by AUG recognition in yeast translation preinitiation complexes Quantitative analysis of mammalian translation initiation sites by FACS-seq Mechanism of cytoplasmic mRNA translation.The β-hairpin of 40S exit channel protein Rps5/uS7 promotes efficient and accurate translation initiation in vivo.Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors.Principles of start codon recognition in eukaryotic translation initiation.Translation complex profile sequencing to study the in vivo dynamics of mRNA-ribosome interactions during translation initiation, elongation and termination.Doubly Spin-Labeled RNA as an EPR Reporter for Studying Multicomponent Supramolecular Assemblies Chemical footprinting reveals conformational changes of 18S and 28S rRNAs at different steps of translation termination on the human ribosome.The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs DHX29 reduces leaky scanning through an upstream AUG codon regardless of its nucleotide context.Heterogeneity of the translational machinery: Variations on a common theme.eIF1A/eIF5B interaction network and its functions in translation initiation complex assembly and remodeling.Enhanced eIF1 binding to the 40S ribosome impedes conformational rearrangements of the preinitiation complex and elevates initiation accuracy.The interaction between eukaryotic initiation factor 1A and eIF5 retains eIF1 within scanning preinitiation complexes.Conserved residues in yeast initiator tRNA calibrate initiation accuracy by regulating preinitiation complex stability at the start codon.Interface between 40S exit channel protein uS7/Rps5 and eIF2α modulates start codon recognition in vivo Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.Interaction of tRNA with eukaryotic ribosome Structural Insights into tRNA Dynamics on the Ribosome.Eukaryotic aspects of translation initiation brought into focus.The integrated stress response.The molecular choreography of protein synthesis: translational control, regulation, and pathways.

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

http://www.wikidata.org/entity/Q27679159

description

2013 nî lūn-bûn

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2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի օգոստոսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

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type

label

The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

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The initiation of mammalian protein synthesis and mRNA scanning mechanism

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Ivan B Lomakin

http://www.w3.org/2001/XMLSchema#string

Thomas A Steitz

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P2860

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

Ribosomal position and contacts of mRNA in eukaryotic translation initiation complexes

Structure and interactions of the translation initiation factor eIF1

PHENIX: a comprehensive Python-based system for macromolecular structure solution

The eIF1A solution structure reveals a large RNA-binding surface important for scanning function

The location of protein S8 and surrounding elements of 16S rRNA in the 70S ribosome from combined use of directed hydroxyl radical probing and X-ray crystallography.

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution

Crystal structure of an initiation factor bound to the 30S ribosomal subunit

Crystal structure of the ribosome at 5.5 A resolution

X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli

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10.1038/NATURE12355

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500

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