Structure of MMACHC reveals an arginine-rich pocket and a domain-swapped dimer for its B12 processing function
about
Navigating the B(12) road: assimilation, delivery, and disorders of cobalaminStructural basis for organohalide respirationMolecular basis of cobalamin-dependent RNA modificationFrom structural biology to designing therapy for inborn errors of metabolismGlutathione-dependent one-electron transfer reactions catalyzed by a B₁₂ trafficking protein.Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling.Structure of Human B12 Trafficking Protein CblD Reveals Molecular Mimicry and Identifies a New Subfamily of Nitro-FMN ReductasesStructural Insights into the MMACHC-MMADHC Protein Complex Involved in Vitamin B12 Trafficking.Novel Deletion Mutation Identified in a Patient with Late-Onset Combined Methylmalonic Acidemia and Homocystinuria, cblC TypeOphthalmic Manifestations and Long-Term Visual Outcomes in Patients with Cobalamin C Deficiency.Milder clinical and biochemical phenotypes associated with the c.482G>A (p.Arg161Gln) pathogenic variant in cobalamin C disease: Implications for management and screening.C-terminal truncation of a bovine B(12) trafficking chaperone enhances the sensitivity of the glutathione-regulated thermostability.Antivitamin B12 Inhibition of the Human B12 -Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate.Coordination chemistry controls the thiol oxidase activity of the B12-trafficking protein CblC.Substrate-mediated control of the conformation of an ancillary domain delivers a competent catalytic site for N-acetylneuraminic acid synthase
P2860
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P2860
Structure of MMACHC reveals an arginine-rich pocket and a domain-swapped dimer for its B12 processing function
description
2012 nî lūn-bûn
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2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
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2012年の論文
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2012年論文
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2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
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name
Structure of MMACHC reveals an ...... or its B12 processing function
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Structure of MMACHC reveals an ...... or its B12 processing function
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Structure of MMACHC reveals an ...... or its B12 processing function
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Structure of MMACHC reveals an ...... or its B12 processing function
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Structure of MMACHC reveals an ...... or its B12 processing function
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Structure of MMACHC reveals an ...... or its B12 processing function
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Structure of MMACHC reveals an ...... or its B12 processing function
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Structure of MMACHC reveals an ...... or its B12 processing function
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D Sean Froese
Roshi Shrestha
Roy A Gravel
Wasim Kiyani
Wyatt W Yue
P304
P3181
P356
10.1021/BI300150Y
P407
P577
2012-06-26T00:00:00Z