Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
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Mechanisms of Hippo pathway regulationRASSF6; the Putative Tumor Suppressor of the RASSF FamilyStructural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathwayPharmacological targeting of kinases MST1 and MST2 augments tissue repair and regenerationDLG5 connects cell polarity and Hippo signaling protein networks by linking PAR-1 with MST1/2MST1/MST2 Protein Kinases: Regulation and Physiologic Roles.Regulation of mammalian Ste20 (Mst) kinases.Hippo Stabilises Its Adaptor Salvador by Antagonising the HECT Ubiquitin Ligase Herc4.Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signalingH-ras Inhibits the Hippo Pathway by Promoting Mst1/Mst2 Heterodimerization.Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM).Integrin α2β1 inhibits MST1 kinase phosphorylation and activates Yes-associated protein oncogenic signaling in hepatocellular carcinoma.Structural dissection of Hippo signaling.Intrinsic protein disorder in oncogenic KRAS signaling.The Role of Embryonic Stem Cell-expressed RAS (ERAS) in the Maintenance of Quiescent Hepatic Stellate Cells.SARAH Domain-Mediated MST2-RASSF Dimeric Interactions.Rassf Proteins as Modulators of Mst1 Kinase Activity.Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex.SAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.The dynamic mechanism of RASSF5 and MST kinase activation by Ras.Cysteine residues are essential for dimerization of Hippo pathway components YAP2L and TAZ.The Hippo Pathway Maintains the Equatorial Division Plane in the Ciliate Tetrahymena.Hras helps hippo heterodimerize to evade tumor suppression.Comparative Modeling, Molecular Docking, and Revealing of Potential Binding Pockets of RASSF2; a Candidate Cancer Gene.Low pH-driven folding of WW45-SARAH domain leads to stabilization of the WW45-Mst2 complex.MST2-RASSF protein-protein interactions through SARAH domains.MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B.Ubiquitin-Dependent Regulation of the Mammalian Hippo Pathway: Therapeutic Implications for Cancer.Hierarchical Organization Endows the Kinase Domain with Regulatory PlasticityActivation mechanisms of the Hippo kinase signaling cascade
P2860
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P2860
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
description
2013 nî lūn-bûn
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2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
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2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@ast
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@en
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@nl
type
label
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@ast
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@en
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@nl
prefLabel
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@ast
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@en
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
Structural Basis for Autoactivation of Human Mst2 Kinase and Its Regulation by RASSF5
@en
P2093
Duojia Pan
Jianzhong Yu
Lisheng Ni
Xuelian Luo
P2860
P304
P3181
P356
10.1016/J.STR.2013.07.008
P577
2013-10-08T00:00:00Z