Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
about
Small Molecule Targeting of Protein-Protein Interactions through Allosteric Modulation of DynamicsAnalysis of worldwide sequence mutations in Zika virus proteins E, NS1, NS3 and NS5 from a structural point of viewNMR and MD Studies Reveal That the Isolated Dengue NS3 Protease Is an Intrinsically Disordered Chymotrypsin Fold Which Absolutely Requests NS2B for Correct Folding and Functional DynamicsA conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease.Solution conformations of Zika NS2B-NS3pro and its inhibition by natural products from edible plantsA small molecule inhibitor of dengue virus type 2 protease inhibits the replication of all four dengue virus serotypes in cell culture.Policresulen, a novel NS2B/NS3 protease inhibitor, effectively inhibits the replication of DENV2 virus in BHK-21 cells.An In-Silico Investigation of Phytochemicals as Antiviral Agents Against Dengue Fever.New developments in flavivirus drug discovery.Inhibition of dengue virus replication by novel inhibitors of RNA-dependent RNA polymerase and protease activities.Conformational flexibility of DENV NS2B/NS3pro: from the inhibitor effect to the serotype influence.An inhibition model of BPTI to unlinked dengue virus NS2B-NS3 protease.The dengue virus NS2B-NS3 protease retains the closed conformation in the complex with BPTI.Binding mode of the activity-modulating C-terminal segment of NS2B to NS3 in the dengue virus NS2B-NS3 protease.In silico study on baicalein and baicalin as inhibitors of dengue virus replication
P2860
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P2860
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@ast
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@en
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@nl
type
label
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@ast
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@en
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@nl
prefLabel
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@ast
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@en
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@nl
P2093
P2860
P356
P1433
P1476
Allosteric Inhibition of the NS2B-NS3 Protease from Dengue Virus
@en
P2093
Jeanne A Hardy
Jeffrey A Bell
Muslum Yildiz
Sumana Ghosh
Woody Sherman
P2860
P304
P356
10.1021/CB400612H
P577
2013-12-20T00:00:00Z