Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction
about
C2ORF29/CNOT11 and CNOT10 form a new module of the CCR4-NOT complexNOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domainStructural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolinHeterogeneity and complexity within the nuclease module of the Ccr4-Not complexThe Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality ControlStructure and RNA-binding properties of the Not1-Not2-Not5 module of the yeast Ccr4-Not complexStructure and assembly of the NOT module of the human CCR4-NOT complexAn asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decayThe structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinaseStructural basis for inhibition of the deadenylase activity of human CNOT6LThe deadenylase components Not2p, Not3p, and Not5p promote mRNA decapping.A genome-wide screening of potential target genes to enhance the antifungal activity of micafungin in Schizosaccharomyces pombeInsights into the structure and architecture of the CCR4-NOT complexNovel roles of the multi-functional CCR4-NOT complex in post-transcriptional regulation.Deadenylation of mRNA by the CCR4-NOT complex in Drosophila: molecular and developmental aspects.Multifunctional roles of the mammalian CCR4-NOT complex in physiological phenomena.The complexity of miRNA-mediated repressionA fluorescence-based assay suitable for quantitative analysis of deadenylase enzyme activity.A highly conserved region essential for NMD in the Upf2 N-terminal domainXenopus CAF1 requires NOT1-mediated interaction with 4E-T to repress translation in vivo.CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteinsThe architecture of the Schizosaccharomyces pombe CCR4-NOT complexBTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferationSystematic identification and correction of annotation errors in the genetic interaction map of Saccharomyces cerevisiae.YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex.The cellular roles of Ccr4-NOT in model and pathogenic fungi-implications for fungal virulenceReconstitution of Targeted Deadenylation by the Ccr4-Not Complex and the YTH Domain Protein Mmi1A feedback mechanism between PLD and deadenylase PARN for the shortening of eukaryotic poly(A) mRNA tails that is deregulated in cancer cells.The diverse roles of the eIF4A family: you are the company you keep.Deadenylation: enzymes, regulation, and functional implications.The role of the E3 ligase Not4 in cotranslational quality control.CCR4 and CAF1 deadenylases have an intrinsic activity to remove the post-poly(A) sequence.Building on the Ccr4-Not architecture.An Ancient Family of RNA-Binding Proteins: Still Important!Architecture of the ubiquitylation module of the yeast Ccr4-Not complex.The Not4 E3 ligase and CCR4 deadenylase play distinct roles in protein quality control.Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAsRoles of mRNA fate modulators Dhh1 and Pat1 in TNRC6-dependent gene silencing recapitulated in yeast.Not4-dependent translational repression is important for cellular protein homeostasis in yeast.Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1.
P2860
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P2860
Architecture of the nuclease module of the yeast Ccr4-not complex: the Not1-Caf1-Ccr4 interaction
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@ast
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@en
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@nl
type
label
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@ast
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@en
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@nl
prefLabel
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@ast
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@en
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@nl
P2093
P50
P3181
P1433
P1476
Architecture of the nuclease m ...... the Not1-Caf1-Ccr4 interaction
@en
P2093
Jérôme Basquin
Michaela Rode
Vladimir V Roudko
P304
P3181
P356
10.1016/J.MOLCEL.2012.08.014
P407
P577
2012-10-26T00:00:00Z