The Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase Druggability - Test2 - elhamkhani - TriplyDB

The Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase Druggability

The Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase Druggability

http://www.wikidata.org/entity/Q27684359

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Evolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode Classification Protein Translation Enzyme lysyl-tRNA Synthetase Presents a New Target for Drug Development against Causative Agents of Loiasis and Schistosomiasis High Throughput Screen Identifies Natural Product Inhibitor of Phenylalanyl-tRNA Synthetase from Pseudomonas aeruginosa and Streptococcus pneumoniae.A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.Discovery and Analysis of Natural-Product Compounds Inhibiting Protein Synthesis in Pseudomonas aeruginosa.Drugging tRNA aminoacylation.

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P2860

The Role of a Novel Auxiliary Pocket in Bacterial Phenylalanyl-tRNA Synthetase Druggability

http://www.wikidata.org/entity/Q27684359

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2014 nî lūn-bûn

@nan

2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

The Role of a Novel Auxiliary ...... l-tRNA Synthetase Druggability

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The Role of a Novel Auxiliary ...... l-tRNA Synthetase Druggability

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The Role of a Novel Auxiliary ...... l-tRNA Synthetase Druggability

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The Role of a Novel Auxiliary ...... l-tRNA Synthetase Druggability

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The Role of a Novel Auxiliary ...... l-tRNA Synthetase Druggability

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The Role of a Novel Auxiliary ...... l-tRNA Synthetase Druggability

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The Role of a Novel Auxiliary ...... l-tRNA Synthetase Druggability

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JBC.M114.574061

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Journal of Biological Chemistry

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The role of a novel auxiliary ...... l-tRNA synthetase druggability

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Andrew D Ferguson

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Ayome Abibi

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D Bryan Prince

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David C McKinney

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Ed T Buurman

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Jun Hu

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Laurel I Hajec

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Ning Gao

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Paul R Fleming

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Sarah M McLeod

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P2860

Human phenylalanyl-tRNA synthetase: cloning, characterization of the deduced amino acid sequences in terms of the structural domains and coordinately regulated expression of the alpha and beta subunits in chronic myeloid leukemia cells

Inhibition of isoleucyl-transfer ribonucleic acid synthetase in Escherichia coli by pseudomonic acid

Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue

Rational protein engineering in action: the first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus

Idiosyncrasy and identity in the prokaryotic phe-system: Crystal structure ofE. coliphenylalanyl-tRNA synthetase complexed with phenylalanine and AMP

In Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzae

Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria

Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus

Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

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