Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4
about
Evolutionary Ecology of Prokaryotic Immune MechanismsProtein crystallization screens developed at the MRC Laboratory of Molecular BiologyApplications of Engineered DNA-Binding Molecules Such as TAL Proteins and the CRISPR/Cas System in Biology ResearchChemical cross-linking and native mass spectrometry: A fruitful combination for structural biologyThe diverse and expanding role of mass spectrometry in structural and molecular biologyStructure Principles of CRISPR-Cas Surveillance and Effector ComplexesDivide and conquer: cleavable cross-linkers to study protein conformation and protein-protein interactions.An Integrated Mass Spectrometry Based Approach to Probe the Structure of the Full-Length Wild-Type Tetrameric p53 Tumor Suppressor.An updated evolutionary classification of CRISPR-Cas systems.C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector.Diverse evolutionary roots and mechanistic variations of the CRISPR-Cas systems.Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex.Cmr4 is the slicer in the RNA-targeting Cmr CRISPR complexMechanism of foreign DNA recognition by a CRISPR RNA-guided surveillance complex from Pseudomonas aeruginosaCrystallization and preliminary X-ray diffraction analysis of the CRISPR-Cas RNA-silencing Cmr complexA Conserved Structural Chassis for Mounting Versatile CRISPR RNA-Guided Immune Responses.Structural biology. Structures of the CRISPR-Cmr complex reveal mode of RNA target positioning.Crystal structures of CRISPR-associated Csx3 reveal a manganese-dependent deadenylation exoribonuclease.The CRISPR-associated Csx1 protein of Pyrococcus furiosus is an adenosine-specific endoribonuclease.Structural basis for the endoribonuclease activity of the type III-A CRISPR-associated protein Csm6Bipartite recognition of target RNAs activates DNA cleavage by the Type III-B CRISPR-Cas systemRNA-activated DNA cleavage by the Type III-B CRISPR-Cas effector complex.Interactomics: toward protein function and regulation.Degradation of Phage Transcripts by CRISPR-Associated RNases Enables Type III CRISPR-Cas Immunity.DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes.Multiple nucleic acid cleavage modes in divergent type III CRISPR systems.Characterization of Runella slithyformis HD-Pnk, a bifunctional DNA/RNA end-healing enzyme composed of an N-terminal 2',3' -phosphoesterase HD domain and a C-terminal 5' -OH polynucleotide kinase domain.A type III-B CRISPR-Cas effector complex mediating massive target DNA destruction.Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry.An archaeal CRISPR type III-B system exhibiting distinctive RNA targeting features and mediating dual RNA and DNA interference.Cmr1 enables efficient RNA and DNA interference of a III-B CRISPR-Cas system by binding to target RNA and crRNA.RNA activation-independent DNA targeting of the Type III CRISPR-Cas system by a Csm complex.Shooting the messenger: RNA-targetting CRISPR-Cas systems.Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell NucleiA Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding
P2860
Q26740457-FD2618FF-365D-4901-BC3E-A8DC43F91C1BQ26749193-11BEDEBD-6F52-4C34-8463-8E061FF0969EQ26781399-2DF34F08-E712-48D4-A166-EDD45F939B5AQ27007533-95BB78EC-5F32-4C0D-AC2B-D1B18C41F781Q28080243-4594BB32-F01D-4C27-BB6C-E0DFDB2F04E3Q28818412-F3520D5B-B0C0-46E9-B796-695DFBE4D2F6Q30313829-D5E87435-40C3-4E13-A3C4-D5FCDDFD3844Q30395774-2C48E5EB-1D05-4D14-B775-E0D926DBCDC4Q33660852-B1AA40D0-BD18-439D-8E60-C9EB852B6577Q34529451-56D2F9D2-077A-4DD0-BCBE-852D81FA0721Q34536517-14D2F19B-F45F-4FEE-8A56-60BDBD2070CFQ34724892-6F980CA2-1251-40CA-B28B-528D289ECEEDQ35098034-BDC79CD8-B8CA-4591-8781-711DD5F12FE5Q35131183-30DEAD06-1783-4820-AFE8-1E0AC927A271Q35705114-DB8EDF9A-7687-4F04-A9A2-211419DBEE20Q35735544-6B64514A-8E5E-4A27-8201-CAB5D49D2F09Q36092029-974387D1-9B7C-4D4E-89E3-FF3E212D0AF9Q36191874-35726B86-5042-44E3-AF23-FEC6B6439B18Q36461912-77AA3B63-CBF0-4432-8114-B6E1F9482632Q36566577-BFCFA36B-F714-445D-A5C9-59B98554B9F9Q36603869-D8916C46-0E17-4322-8092-87433FE4E10BQ36603874-E66245E2-3BF6-4C8A-BD65-76F2FC043A5AQ38314132-B246C2FE-7B15-4F88-9D4E-02E99C724766Q38412720-A3D31114-A386-480C-8749-C2A002AFA956Q38454128-DCD307AC-91AB-4E13-8FB1-6DAF4AAEEB8CQ38667891-166CADE8-9C62-41AD-9E1F-7D012533441EQ39147497-29B59E2C-3364-46CF-9F61-A47C22F36652Q40420402-EE81B30B-DD1F-4AA8-826A-0E66103F9A13Q40492197-6F51162C-DDAD-4868-873A-B6BE2DDB6553Q43097718-6537C94A-9CE1-4B95-A25F-1A27BD2F6192Q47104208-D0F34FC4-313F-4937-B663-E3777149CEA7Q48340130-2B6EED94-1EF2-4086-94FE-E71F278F006FQ55436015-B464E909-4F5E-4094-8EE6-B7C4644C9C5DQ57143674-29F33DC9-F172-42F0-8560-2623296EE23BQ58708478-D74AED83-F57B-49ED-A1D3-A722D07D2DBE
P2860
Structural model of a CRISPR RNA-silencing complex reveals the RNA-target cleavage activity in Cmr4
description
2014 nî lūn-bûn
@nan
2014 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@ast
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@en
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@nl
type
label
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@ast
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@en
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@nl
prefLabel
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@ast
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@en
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@nl
P2093
P3181
P1433
P1476
Structural model of a CRISPR R ...... rget cleavage activity in Cmr4
@en
P2093
Christian Benda
Herbert B Schiller
Judith Ebert
Marc Baumgärtner
Matthias Mann
Richard A Scheltema
P3181
P356
10.1016/J.MOLCEL.2014.09.002
P577
2014-10-02T00:00:00Z