A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications
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NMR Fragment Screening Hit Induces Plasticity of BRD7/9 BromodomainsSelective BET bromodomain inhibition as an antifungal therapeutic strategyTargeting the Bromome: are we there yet?The polar warhead of a TRIM24 bromodomain inhibitor rearranges a water-mediated interaction network.YEATS domain: Linking histone crotonylation to gene regulation.Chemical probes targeting epigenetic proteins: Applications beyond oncology.The Taf14 YEATS domain is a reader of histone crotonylation.Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS DomainDynamic Competing Histone H4 K5K8 Acetylation and Butyrylation Are Hallmarks of Highly Active Gene Promoters.YEATS2 is a selective histone crotonylation reader.Multifaceted Histone H3 Methylation and Phosphorylation Readout by the Plant Homeodomain Finger of Human Nuclear Antigen Sp100C.Expression and epigenomic landscape of the sex chromosomes in mouse post-meiotic male germ cells.Insights into newly discovered marks and readers of epigenetic information.Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2.Epigenomic regulation of oncogenesis by chromatin remodeling.Biological function and histone recognition of family IV bromodomain-containing proteins.Selectivity on-target of bromodomain chemical probes by structure-guided medicinal chemistry and chemical biology.Diverse Activities of Histone Acylations Connect Metabolism to Chromatin Function.Structural features and inhibitors of bromodomains.Metabolic regulation of gene expression through histone acylations.The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets.Histone Post-Translational Modifications and Nucleosome Organisation in Transcriptional Regulation: Some Open Questions.Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS DomainBRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors.Expanding the Reader Landscape of Histone Acylation.Molecular structures guide the engineering of chromatin.Non-canonical reader modules of BAZ1A promote recovery from DNA damage.Reading and Interpreting the Histone Acylation Code.Protein dynamics and structural waters in bromodomains.Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway.Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.Structure of p300 in complex with acyl-CoA variants.Large-scale analysis of water stability in bromodomain binding pockets with grand canonical Monte Carlo
P2860
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P2860
A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications
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2015 nî lūn-bûn
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2015 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հոտեմբերին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
@zh-mo
2015年論文
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2015年论文
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name
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@ast
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@en
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@nl
type
label
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@ast
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@en
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@nl
prefLabel
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@ast
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@en
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@nl
P2093
P3181
P1433
P1476
A Subset of Human Bromodomains ...... Histone Peptide Modifications
@en
P2093
E Megan Flynn
Florence Poy
Mariano Oppikofer
Oscar W Huang
Steve F Bellon
P304
P3181
P356
10.1016/J.STR.2015.08.004
P577
2015-10-06T00:00:00Z