Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog
about
Three decades of beta-lactamase inhibitorsThe complexed structure and antimicrobial activity of a non-β-lactam inhibitor of AmpC β-lactamaseEstB from Burkholderia gladioli: A novel esterase with a β-lactamase fold reveals steric factors to discriminate between esterolytic and β-lactam cleaving activityStructural basis for imipenem inhibition of class C beta-lactamases.Hydrolysis of third-generation cephalosporins by class C beta-lactamases. Structures of a transition state analog of cefotoxamine in wild-type and extended spectrum enzymesStructure-based optimization of cephalothin-analogue boronic acids as β-lactamase inhibitorsRe-examining the role of Lys67 in class C β-lactamase catalysisStructure of AmpC β-lactamase (AmpCD) from anEscherichia coliclinical isolate with a tripeptide deletion (Gly286-Ser287-Asp288) in the H10 helixDesign, Synthesis, Crystal Structures, and Antimicrobial Activity of Sulfonamide Boronic Acids as β-Lactamase InhibitorsStructure of the extended-spectrum class C β-lactamase ADC-1 fromAcinetobacter baumanniiStructural analysis of the Asn152Gly mutant of P99 cephalosporinaseCrystal Structure of Mox-1, a Unique Plasmid-Mediated Class C -Lactamase with Hydrolytic Activity towards MoxalactamAvibactam and Class C -Lactamases: Mechanism of Inhibition, Conservation of the Binding Pocket, and Implications for ResistanceStructural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathwayCrystal structure analysis of EstA from Arthrobacter sp. Rue61a--an insight into catalytic promiscuityCrystal structure of D-stereospecific amidohydrolase from Streptomyces sp. 82F2 - insight into the structural factors for substrate specificityHotSpot Wizard: a web server for identification of hot spots in protein engineering.Kinetics and mechanism of inhibition of a serine beta-lactamase by O-aryloxycarbonyl hydroxamatespKa measurements from nuclear magnetic resonance of tyrosine-150 in class C beta-lactamase.Identification of residues critical for catalysis in a class C beta-lactamase by combinatorial scanning mutagenesis.The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution.Towards a ligand targeted enzyme prodrug therapy: single round panning of a beta-lactamase scaffold library on human cancer cells.Inhibition of OXA-1 beta-lactamase by penems.A new family of cyanobacterial penicillin-binding proteins. A missing link in the evolution of class A beta-lactamases.Developing bifunctional beta-lactamase molecules with built-in target-recognizing module for prodrug therapy: identification of Enterobacter Cloacae P99 cephalosporinase loops suitable for randomization and phage-display selection.Inhibition of the class C beta-lactamase from Acinetobacter spp.: insights into effective inhibitor design.Substituted aryl malonamates as new serine beta-lactamase substrates: structure-activity studiesKinship and diversification of bacterial penicillin-binding proteins and beta-lactamases.Inhibition of class A and C beta-lactamases by diaroyl phosphates.Permeation through the cell membrane of a boron-based β-lactamase inhibitor.Structure, function, and inhibition along the reaction coordinate of CTX-M beta-lactamases.Serendipitous discovery of α-hydroxyalkyl esters as β-lactamase substrates.Exploring sequence requirements for C₃/C₄ carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase.Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure.Beta-lactamase inhibitors: evolving compounds for evolving resistance targets.B1-Metallo-β-Lactamases: Where Do We Stand?Development of new drugs for an old target: the penicillin binding proteins.Structural and mechanistic insights into the inhibition of class C β-lactamases through the adenylylation of the nucleophilic serine.Structure-function studies of Ser-289 in the class C beta-lactamase from Enterobacter cloacae P99.Beta-lactamases and bacterial resistance to antibiotics.
P2860
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P2860
Crystallographic structure of a phosphonate derivative of the Enterobacter cloacae P99 cephalosporinase: mechanistic interpretation of a beta-lactamase transition-state analog
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Crystallographic structure of ...... tamase transition-state analog
@ast
Crystallographic structure of ...... tamase transition-state analog
@en
Crystallographic structure of ...... tamase transition-state analog
@nl
type
label
Crystallographic structure of ...... tamase transition-state analog
@ast
Crystallographic structure of ...... tamase transition-state analog
@en
Crystallographic structure of ...... tamase transition-state analog
@nl
prefLabel
Crystallographic structure of ...... tamase transition-state analog
@ast
Crystallographic structure of ...... tamase transition-state analog
@en
Crystallographic structure of ...... tamase transition-state analog
@nl
P2093
P356
P1433
P1476
Crystallographic structure of ...... tamase transition-state analog
@en
P2093
P304
P356
10.1021/BI00188A004
P407
P577
1994-06-07T00:00:00Z