Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II
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Retrostructural analysis of metalloproteins: application to the design of a minimal model for diiron proteinsZinc Coordination Geometry and Ligand Binding Affinity: The Structural and Kinetic Analysis of the Second-Shell Serine 228 Residue and the Methionine 180 Residue of the Aminopeptidase from Vibrio proteolyticus †High-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug designDesigning hydrolytic zinc metalloenzymesExploring local flexibility/rigidity in psychrophilic and mesophilic carbonic anhydrases.Coupling Protein Dynamics with Proton Transport in Human Carbonic Anhydrase II.Carbonic anhydrase II-based metal ion sensing: Advances and new perspectives.Long wavelength fluorescence ratiometric zinc biosensor.Computational design of a Zn2+ receptor that controls bacterial gene expression.Quantitative imaging of mitochondrial and cytosolic free zinc levels in an in vitro model of ischemia/reperfusion.Selection of carbonic anhydrase variants displayed on phage. Aromatic residues in zinc binding site enhance metal affinity and equilibration kinetics.Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.Carbonic anhydrases and their biotechnological applications.Mutations at nonliganding residues Tyr-85 and Glu-83 in the N-lobe of human serum transferrin. Functional second shell effects.Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants.Kinetics and thermodynamics of metal-binding to histone deacetylase 8.Definition of the interaction domain for cytochrome c on cytochrome c oxidase. III. Prediction of the docked complex by a complete, systematic search.The activity and cofactor preferences of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) change depending on environmental conditions.Metal-histidine-glutamate as a regulator of enzymatic cycles: a case study of carbonic anhydrase.Catalytic activity of a ζ-class zinc and cadmium containing carbonic anhydrase. Compared work mechanisms.Mobile trap algorithm for zinc detection using protein sensors.Augmented hydrolysis of diisopropyl fluorophosphate in engineered mutants of phosphotriesterase.Role of a remote leucine residue in the catalytic function of polyol dehydrogenase.Neurotoxicity Linked to Dysfunctional Metal Ion Homeostasis and Xenobiotic Metal Exposure: Redox Signaling and Oxidative Stress
P2860
Q27622718-7F131E8A-ABC3-41CD-81E2-CA0179B37278Q27650934-4B0AE5B0-6A89-4281-B98A-35A2477B30DAQ27657938-BDBD33EF-DF11-40D8-9C1F-BF460E314E67Q30358793-02D29C21-4F13-40A3-ACD6-518B1A8E36D9Q30374943-A15450E5-1428-41FB-A6E5-F4B3B17AFD2AQ30804652-03927F91-A438-4BF8-962A-101628C3724CQ33637489-DD4D11F8-5623-438B-AD5A-26D789BF1B1FQ34560405-5ED60F1B-C86B-4611-AB7C-3DFB039F8B92Q36160612-09696D5A-28CF-48FA-8831-7931A27D6BFFQ36517190-F0EA0290-65C5-4FF3-A232-32F9DBFFEF3DQ36875622-0CB62088-F538-46F7-B43E-2D306B238DC9Q37108161-77A64439-16A0-4D79-9CA2-12BAC22C2C9FQ38223680-7E68499E-524C-4B78-AB05-1380ED7AE023Q38336109-08F21A73-10CE-4ABD-908D-D0AF3CE88D76Q40145551-66762A35-F973-43A9-9B79-1B18ADA2C772Q41680639-C57A9C50-B6BD-4A41-B149-AE8864347776Q41710393-00734F8F-322A-4F32-912A-4BB064A541E0Q41810835-D713889A-5AF5-4B1F-B965-179EE47A5B5BQ46194663-AE18C367-00FB-499B-B2A3-8F96FF3C41EEQ47329836-D5A566A2-6CDC-4548-8164-C19F249BC290Q50860783-AF282168-0A4E-4E76-B3F6-741883C1AB89Q52559249-E3725FEB-87E6-4C04-B0DD-2EBF263F7BD3Q53421901-772AB4AF-67BE-4FAD-B3EA-4380D26C87D2Q57649750-3D5F43EA-F0BC-43C6-979B-7656D3FD645F
P2860
Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II
description
1996 nî lūn-bûn
@nan
1996 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մարտին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@ast
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@en
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@nl
type
label
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@ast
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@en
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@nl
prefLabel
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@ast
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@en
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@nl
P2093
P356
P1433
P1476
Reversal of the hydrogen bond ...... etics in carbonic anhydrase II
@en
P2093
C A Fierke
C A Lesburg
D W Christianson
L L Kiefer
P304
P356
10.1021/BI9526692
P407
P577
1996-03-19T00:00:00Z