A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
about
Conserved residues of human XPG protein important for nuclease activity and function in nucleotide excision repairMolecular interactions of human Exo1 with DNAArginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determinationHex1: a new human Rad2 nuclease family member with homology to yeast exonuclease 1Biochemical analyses indicate that binding and cleavage specificities define the ordered processing of human Okazaki fragments by Dna2 and FEN1The 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysisDouble strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamilyUnpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleasesThe crystal structure of exonuclease RecJ bound to Mn2+ ion suggests how its characteristic motifs are involved in exonuclease activityMolecular structure and novel DNA binding sites located in loops of flap endonuclease-1 from Pyrococcus horikoshiiDistant structural homology leads to the functional characterization of an archaeal PIN domain as an exonucleaseCrystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substratesCrystal structure of PAE0151 from Pyrobaculum aerophilum, a PIN-domain (VapC) protein from a toxin-antitoxin operonStructure of flap endonuclease 1 from the hyperthermophilic archaeonDesulfurococcus amylolyticusStructures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease FamilyThe structure of Escherichia coli ExoIX--implications for DNA binding and catalysis in flap endonucleasesStructural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNaseSRP RNA remodeling by SRP68 explains its role in protein translocationThe crystal structure of flap endonuclease-1 from Methanococcus jannaschiiMutagenesis of conserved lysine residues in bacteriophage T5 5'-3' exonuclease suggests separate mechanisms of endo-and exonucleolytic cleavageSaccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nucleaseCleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate.Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation.A novel DNA-binding motif shares structural homology to DNA replication and repair nucleases and polymerasesEnzymes and reactions at the eukaryotic DNA replication forkMechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1Direct observation of DNA threading in flap endonuclease complexesThe protein components and mechanism of eukaryotic Okazaki fragment maturation.Molecular interactions of Escherichia coli ExoIX and identification of its associated 3'-5' exonuclease activity.Structure-specific DNA-induced conformational changes in Taq polymerase revealed by small angle neutron scattering.Common fold in helix-hairpin-helix proteins.Dna2 is a structure-specific nuclease, with affinity for 5'-flap intermediates.Methanococcus jannaschii flap endonuclease: expression, purification, and substrate requirementsA model for transition of 5'-nuclease domain of DNA polymerase I from inert to active modesUnusually wide co-factor tolerance in a metalloenzyme; divalent metal ions modulate endo-exonuclease activity in T5 exonuclease.Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis.Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavageInteractions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding.The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.Flap endonuclease 1 mechanism analysis indicates flap base binding prior to threading
P2860
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P2860
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
description
1996 nî lūn-bûn
@nan
1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@ast
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@en
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@nl
type
label
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@ast
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@en
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@nl
prefLabel
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@ast
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@en
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@nl
P2093
P356
P1433
P1476
A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease
@en
P2093
P2888
P356
10.1038/382090A0
P407
P577
1996-07-01T00:00:00Z
P6179
1014222955