Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis
about
The crystal structure of human transketolase and new insights into its mode of actionSnapshot of a key intermediate in enzymatic thiamin catalysis: crystal structure of the alpha-carbanion of (alpha,beta-dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiaeStructure and Properties of an Engineered Transketolase from MaizeCrystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathwayCrystal Structures of Phosphoketolase: THIAMINE DIPHOSPHATE-DEPENDENT DEHYDRATION MECHANISMStructure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzymeExamination of donor substrate conversion in yeast transketolase.1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus.Directed evolution to re-adapt a co-evolved network within an enzyme.A candidate gene association study on muscat flavor in grapevine (Vitis vinifera L.).A thermostable transketolase evolved for aliphatic aldehyde acceptors.Second-Generation Engineering of a Thermostable Transketolase (TKGst ) for Aliphatic Aldehyde Acceptors with Either Improved or Reversed Stereoselectivity.Plasmid-dependent methylotrophy in thermotolerant Bacillus methanolicusUsing site-saturation mutagenesis to explore mechanism and substrate specificity in thiamin diphosphate-dependent enzymes.Engineering stereoselectivity of ThDP-dependent enzymes.Investigating strain dependency in the production of aromatic compounds in Saccharomyces cerevisiae.Transketolase from Leishmania mexicana has a dual subcellular localization.Isolable analogues of the Breslow intermediate derived from chiral triazolylidene carbenes.Thiamin Diphosphate Activation in 1-Deoxy-d-xylulose 5-Phosphate Synthase: Insights into the Mechanism and Underlying Intermolecular InteractionsHigh-resolution structures of Lactobacillus salivarius transketolase in the presence and absence of thiamine pyrophosphateCatalytic asymmetric cross-aza-benzoin reactions of aliphatic aldehydes with N-Boc-protected imines.Critical role of arg433 in rat transketolase activity as probed by site-directed mutagenesis.Phage Display on the Anti-infective Target 1-Deoxy-d-xylulose-5-phosphate Synthase Leads to an Acceptor-Substrate Competitive Peptidic Inhibitor.Structural and biochemical interrogation on transketolase from Pichia stipitis for new functionality.Mechanistic Studies of 1-Deoxy-D-Xylulose-5-Phosphate Synthase from Deinococcus radiodurans.Crystal structure of 1-deoxy-D-xylulose 5-phosphate synthase, a crucial enzyme for isoprenoids biosynthesis.Asp477 is a determinant of the enantioselectivity in yeast transketolase
P2860
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P2860
Examination of substrate binding in thiamin diphosphate-dependent transketolase by protein crystallography and site-directed mutagenesis
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Examination of substrate bindi ...... and site-directed mutagenesis
@ast
Examination of substrate bindi ...... and site-directed mutagenesis
@en
Examination of substrate bindi ...... and site-directed mutagenesis
@nl
type
label
Examination of substrate bindi ...... and site-directed mutagenesis
@ast
Examination of substrate bindi ...... and site-directed mutagenesis
@en
Examination of substrate bindi ...... and site-directed mutagenesis
@nl
prefLabel
Examination of substrate bindi ...... and site-directed mutagenesis
@ast
Examination of substrate bindi ...... and site-directed mutagenesis
@en
Examination of substrate bindi ...... and site-directed mutagenesis
@nl
P2860
P356
P1476
Examination of substrate bindi ...... and site-directed mutagenesis
@en
P2093
L Meshalkina
P2860
P304
P356
10.1074/JBC.272.3.1864
P407
P577
1997-01-17T00:00:00Z