Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7
about
The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycleRb inhibits the intrinsic kinase activity of TATA-binding protein-associated factor TAFII250Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteinsCells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycleThe de-ubiquitinating enzyme Unp interacts with the retinoblastoma proteinStructure of the human Papillomavirus E7 oncoprotein and its mechanism for inactivation of the retinoblastoma tumor suppressorTargeting mechanism of the retinoblastoma tumor suppressor by a prototypical viral oncoprotein. Structural modularity, intrinsic disorder and phosphorylation of human papillomavirus E7p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosisDeacetylation of the retinoblastoma tumour suppressor protein by SIRT1RNA polymerase III transcription factor IIIB is a target for repression by pocket proteins p107 and p130.RBP1 recruits both histone deacetylase-dependent and -independent repression activities to retinoblastoma family proteinsRING3 kinase transactivates promoters of cell cycle regulatory genes through E2FSensitive and efficient detection of RB1 gene mutations enhances care for families with retinoblastomaTumor suppressors: enhancers or suppressors of regeneration?Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressorThe retinoblastoma family: twins or distant cousins?Conserved and specific functions of mammalian ssu72RB1 gene mutation up-date, a meta-analysis based on 932 reported mutations available in a searchable database.The association of mammalian DREAM complex and HPV16 E7 proteinsPP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues.PP1 and PP2A phosphatases--cooperating partners in modulating retinoblastoma protein activationMolecular mechanisms underlying RB protein functionDisruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancerDown-regulation of the retinoblastoma tumor suppressor by the hepatitis C virus NS5B RNA-dependent RNA polymeraseA Locking Mechanism Regulates RNA Synthesis and Host Protein Interaction by the Hepatitis C Virus PolymeraseStructural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigenCrystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulationThe crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53The structure of the AXH domain of spinocerebellar ataxin-1Crystal structure of the homolog of the oncoprotein gankyrin, an interactor of Rb and CDK4/6Structure of the retinoblastoma protein bound to adenovirus E1A reveals the molecular basis for viral oncoprotein inactivation of a tumor suppressorCrystal Structure of the Retinoblastoma Protein N Domain Provides Insight into Tumor Suppression, Ligand Interaction, and Holoprotein ArchitectureStructural basis for subversion of cellular control mechanisms by the adenoviral E1A oncoproteinCrystal structure of the unliganded retinoblastoma protein pocket domainStructures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle controlAPC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathwayPhysical interaction between pRb and cdk9/cyclinT2 complexDisruption of BRCA1 LXCXE motif alters BRCA1 functional activity and regulation of RB family but not RB protein bindingpRb2/p130: a new candidate for retinoblastoma tumor formationMolecular determinants for the complex formation between the retinoblastoma protein and LXCXE sequences
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P2860
Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@ast
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@en
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@nl
type
label
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@ast
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@en
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@nl
prefLabel
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@ast
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@en
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@nl
P2093
P2860
P3181
P356
P1433
P1476
Structure of the retinoblastom ...... bound to a peptide from HPV E7
@en
P2093
P2860
P2888
P304
P3181
P356
10.1038/36038
P407
P577
1998-02-26T00:00:00Z
P6179
1025597222