Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base
about
Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI-DNA complexesStructural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteriaA dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivoDNA binding properties in vivo and target recognition domain sequence alignment analyses of wild-type and mutant RsrI [N6-adenine] DNA methyltransferases.Metadynamics simulation study on the conformational transformation of HhaI methyltransferase: an induced-fit base-flipping hypothesisStructural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6A dual role for substrate S-adenosyl-L-methionine in the methylation reaction with bacteriophage T4 Dam DNA-[N6-adenine]-methyltransferase.AdoMet-dependent methylation, DNA methyltransferases and base flipping.Low-frequency normal mode in DNA HhaI methyltransferase and motions of residues involved in the base flipping.Molecular and enzymatic profiles of mammalian DNA methyltransferases: structures and targets for drugs.Inhibition of (cytosine C5)-methyltransferase by oligonucleotides containing flexible (cyclopentane) and conformationally constrained (bicyclo[3.1.0]hexane) abasic sites.DNA bending and unbending by MutS govern mismatch recognition and specificityModification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix.Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases.A molecular dynamics study of slow base flipping in DNA using conformational floodingChemical mapping of cytosines enzymatically flipped out of the DNA helix.Crystallization and preliminary crystallographic analysis of the (cytosine-5)-DNA methyltransferase NlaX from Neisseria lactamica.Nucleoprotein assemblies at the nanoscale: medical implications.DNA cytosine methylation: structural and thermodynamic characterization of the epigenetic marking mechanism.6-Thioguanine perturbs cytosine methylation at the CpG dinucleotide site by DNA methyltransferases in vitro and acts as a DNA demethylating agent in vivo.Caught in the act: visualization of an intermediate in the DNA base-flipping pathway induced by HhaI methyltransferaseDNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site.Presteady-state analysis of a single catalytic turnover by Escherichia coli uracil-DNA glycosylase reveals a "pinch-pull-push" mechanism.Water-assisted dual mode cofactor recognition by HhaI DNA methyltransferase.The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase.Reconciling structure and function in HhaI DNA cytosine-C-5 methyltransferase.DNA mismatch-specific base flipping by a bisacridine macrocycle.Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors.Substrate binding in vitro and kinetics of RsrI [N6-adenine] DNA methyltransferaseMutational analysis of conserved residues in HhaI DNA methyltransferaseSolution structure of a nitrous acid induced DNA interstrand cross-link.Sequence context effect on the structure of nitrous acid induced DNA interstrand cross-linksThe NMR structure of an internal loop from 23S ribosomal RNA differs from its structure in crystals of 50s ribosomal subunitsSpecific targeting of cytosine methylation to DNA sequences in vivo.The coupling of tight DNA binding and base flipping: identification of a conserved structural motif in base flipping enzymes.An electrical probe of protein-DNA interactions on DNA-modified surfaces.Flipping duplex DNA inside out: a double base-flipping reaction mechanism by Escherichia coli MutY adenine glycosylase.Residues distal from the active site that alter enzyme function in M.HhaI DNA cytosine methyltransferase.Spontaneous base flipping in DNA and its possible role in methyltransferase binding.Structure and dynamics of H. pylori 98-10 C5-cytosine specific DNA methyltransferase in complex with S-adenosyl-l-methionine and DNA.
P2860
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P2860
Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Structures of HhaI methyltrans ...... mismatches at the target base
@ast
Structures of HhaI methyltrans ...... mismatches at the target base
@en
Structures of HhaI methyltrans ...... mismatches at the target base
@nl
type
label
Structures of HhaI methyltrans ...... mismatches at the target base
@ast
Structures of HhaI methyltrans ...... mismatches at the target base
@en
Structures of HhaI methyltrans ...... mismatches at the target base
@nl
prefLabel
Structures of HhaI methyltrans ...... mismatches at the target base
@ast
Structures of HhaI methyltrans ...... mismatches at the target base
@en
Structures of HhaI methyltrans ...... mismatches at the target base
@nl
P2860
P356
P1476
Structures of HhaI methyltrans ...... mismatches at the target base
@en
P2093
P2860
P304
P356
10.1038/2312
P577
1998-10-01T00:00:00Z