An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
about
Machine learning helps identify CHRONO as a circadian clock componentActivating PER repressor through a DBT-directed phosphorylation switchDelayed sleep phase cases and controlsHigh-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinaseModeling of a human circadian mutation yields insights into clock regulation by PER2SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) proteinProtein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clockCircadian genes in a blind subterranean mammal II: conservation and uniqueness of the three Period homologs in the blind subterranean mole rat, Spalax ehrenbergi superspeciesThe circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase IepsilonNEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speedTherapeutics for Circadian Rhythm Sleep DisordersDrosophila doubletime mutations which either shorten or lengthen the period of circadian rhythms decrease the protein kinase activity of casein kinase IProtein malnutrition during pregnancy in C57BL/6J mice results in offspring with altered circadian physiology before obesityGenetics of sleep and sleep disordersSetting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteinsA common polymorphism near PER1 and the timing of human behavioral rhythmsCircadian organization of behavior and physiology in DrosophilaThe transcriptional repressor DEC2 regulates sleep length in mammalsControl of sleep and wakefulnessThe period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1History of the development of sleep medicine in the United StatesViral infection and human disease--insights from minimotifsInter-individual differences in habitual sleep timing and entrained phase of endogenous circadian rhythms of BMAL1, PER2 and PER3 mRNA in human leukocytesCasein kinase 1 delta regulates the pace of the mammalian circadian clockDifferential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)Circadian rhythm sleep disorders: part II, advanced sleep phase disorder, delayed sleep phase disorder, free-running disorder, and irregular sleep-wake rhythm. An American Academy of Sleep Medicine reviewA small conserved domain of Drosophila PERIOD is important for circadian phosphorylation, nuclear localization, and transcriptional repressor activityToward a detailed computational model for the mammalian circadian clockPhosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clockTranscriptional oscillation of canonical clock genes in mouse peripheral tissuesHuman molecular chronotyping in sight?The period length of fibroblast circadian gene expression varies widely among human individualsAssociation of the Period3 clock gene length polymorphism with salivary cortisol secretion among police officersCircadian Dysrhythmias, Physiological Aberrations, and the Link to Skin CancerPost-transcriptional control of the mammalian circadian clock: implications for health and diseaseInterdependence of nutrient metabolism and the circadian clock system: Importance for metabolic healthThe Impact of Melatonin in ResearchCircadian rhythms and mood: opportunities for multi-level analyses in genomics and neuroscience: circadian rhythm dysregulation in mood disorders provides clues to the brain's organizing principles, and a touchstone for genomics and neuroscienceNew technologies for integrating genomic, environmental and trait dataGenetic basis of human circadian rhythm disorders
P2860
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P2860
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@ast
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@en
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@nl
type
label
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@ast
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@en
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@nl
altLabel
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome
@en
prefLabel
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@ast
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@en
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@nl
P2093
P3181
P356
P1433
P1476
An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome.
@en
P2093
D M Virshup
L J Ptácek
P304
P3181
P356
10.1126/SCIENCE.1057499
P407
P577
2001-02-09T00:00:00Z