Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy.
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The RUN domain of rubicon is important for hVps34 binding, lipid kinase inhibition, and autophagy suppressionPtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ.Autophagy: molecular machinery for self-eatingPhosphoinositides: tiny lipids with giant impact on cell regulationAtg27 is required for autophagy-dependent cycling of Atg9Immunoisolaton of the yeast Golgi subcompartments and characterization of a novel membrane protein, Svp26, discovered in the Sed5-containing compartments.Atg21 is required for effective recruitment of Atg8 to the preautophagosomal structure during the Cvt pathway.Vps51 is part of the yeast Vps fifty-three tethering complex essential for retrograde traffic from the early endosome and Cvt vesicle completion.GSK-3beta activity is increased in skeletal muscle after burn injury in ratsThe evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolismBeclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAGTraffic to the malaria parasite food vacuole: a novel pathway involving a phosphatidylinositol 3-phosphate-binding proteinGenomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiaeAutophagy in unicellular eukaryotesThe molecular mechanism of autophagy.Mitochondria autophagy in yeast.Mutant fibrinogen cleared from the endoplasmic reticulum via endoplasmic reticulum-associated protein degradation and autophagy: an explanation for liver disease.The molecular machinery of autophagy: unanswered questions.The phospholipase D1 pathway modulates macroautophagyReceptor-mediated Endocytosis 8 Utilizes an N-terminal Phosphoinositide-binding Motif to Regulate Endosomal Clathrin Dynamics.PI4P-signaling pathway for the synthesis of a nascent membrane structure in selective autophagy.Molecular mechanism and regulation of autophagy.Thioredoxin and thioredoxin target proteins: from molecular mechanisms to functional significance.Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiaeSignal transduction pathways that contribute to myeloid differentiation.PTEN and the PI3-kinase pathway in cancerThe yeast lysosome-like vacuole: endpoint and crossroadsInterconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development.The phosphoinositide 3-kinase pathway in human cancer: genetic alterations and therapeutic implications.Role of macroautophagy in nutrient homeostasis during fungal development and pathogenesis.Dopamine- and zinc-induced autophagosome formation facilitates PC12 cell survival.The expression of damage-regulated autophagy modulator 2 (DRAM2) contributes to autophagy induction.Bacteria-generated PtdIns(3)P recruits VAMP8 to facilitate phagocytosis.Amino acids interfere with the ERK1/2-dependent control of macroautophagy by controlling the activation of Raf-1 in human colon cancer HT-29 cells.TMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9AS. pombe btn1, the orthologue of the Batten disease gene CLN3, is required for vacuole protein sorting of Cpy1p and Golgi exit of Vps10p.Pdr5-mediated multidrug resistance requires the CPY-vacuolar sorting protein Vps3: are xenobiotic compounds routed from the vacuole to plasma membrane transporters for efflux?Leucine mediates autophagosome-lysosome fusion and improves sperm motility by activating the PI3K/Akt pathway.Vps15p regulates the distribution of cup-shaped organelles containing the major eisosome protein Pil1p to the extracellular fraction required for endocytosis of extracellular vesicles carrying metabolic enzymes.
P2860
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P2860
Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy.
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@ast
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@en
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@nl
type
label
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@ast
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@en
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@nl
altLabel
Novel PtdIns(3)P-binding prote ...... 4 PtdIns 3-kinase in autophagy
@en
prefLabel
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@ast
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@en
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@nl
P2860
P356
P1476
Novel PtdIns(3)P-binding prote ...... PtdIns 3-kinase in autophagy.
@en
P2093
Andrew E Wurmser
Scott D Emr
P2860
P304
P356
10.1083/JCB.200112050
P407
P577
2002-08-19T00:00:00Z