Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex
about
The dynamic dimerization of the yeast ADP/ATP carrier in the inner mitochondrial membrane is affected by conserved cysteine residues.Mia40 is a trans-site receptor that drives protein import into the mitochondrial intermembrane space by hydrophobic substrate binding.Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins.The essential function of Tim12 in vivo is ensured by the assembly interactions of its C-terminal domain.The channel-forming Sym1 protein is transported by the TIM23 complex in a presequence-independent mannerAssembly of Tim9 and Tim10 into a functional chaperone.Juxtaposition of the two distal CX3C motifs via intrachain disulfide bonding is essential for the folding of Tim10.Reconstituted TOM core complex and Tim9/Tim10 complex of mitochondria are sufficient for translocation of the ADP/ATP carrier across membranes.The Tim9p-Tim10p complex binds to the transmembrane domains of the ADP/ATP carrierHsp90 functions in the targeting and outer membrane translocation steps of Tom70-mediated mitochondrial import.The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein importPrecursor oxidation by Mia40 and Erv1 promotes vectorial transport of proteins into the mitochondrial intermembrane space.Mitochondrial import of the ADP/ATP carrier: the essential TIM complex of the intermembrane space is required for precursor release from the TOM complex.Rapid regulation of steroidogenesis by mitochondrial protein import.Zinc-dependent intermembrane space proteins stimulate import of carrier proteins into plant mitochondria.Functional TIM10 chaperone assembly is redox-regulated in vivo.The structural basis of the TIM10 chaperone assembly.Oxidative folding of small Tims is mediated by site-specific docking onto Mia40 in the mitochondrial intermembrane space
P2860
Q27930113-23BB2116-E225-45A1-A519-AF94BBFAE536Q27934445-7E6B4C4D-4DAF-4F3F-BECE-BCF3C611A718Q27936684-DE6B2D8D-FAD8-474B-A04A-4144EB3DE387Q27937298-E259FF12-D87D-4823-BBE0-407EE5B886F3Q27938469-3C5ECC79-347E-4214-9C48-4A3BE1569C66Q27938777-FB57A3C0-1CFF-4B35-86E6-5373B4B89791Q30969937-11233244-149A-44EB-B6FF-D57BA6D18656Q31032213-903A71D6-736F-453E-B7F1-07E0C6C2ACB0Q34086079-5DE5B454-F342-4825-B513-5DF51128A88AQ34565583-A111D230-D441-4210-A745-05B5AEC97CF3Q35613439-BA14FC04-CF3B-4EBB-9571-F8EC942D9CB0Q36325895-13C50B6D-9063-4302-9DFD-4B4271FA5AEAQ39677851-C85B7F37-01F5-4243-958D-EF25FAAB8083Q43447990-13C36CEA-5995-440E-8C35-1E7AD49957DEQ44016523-7C62D625-F8C6-474E-9AB4-8B32328FE28DQ44770006-40BD17EF-EEC0-4C55-BBA3-46646282507DQ47197538-F84DFAE4-7504-4B21-9EAB-E4B7013E10A4Q57832371-C4ED948D-9118-44B4-9AC3-20ABDF540ADF
P2860
Functional reconstitution of the import of the yeast ADP/ATP carrier mediated by the TIM10 complex
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Functional reconstitution of t ...... mediated by the TIM10 complex
@ast
Functional reconstitution of t ...... mediated by the TIM10 complex
@en
Functional reconstitution of t ...... mediated by the TIM10 complex.
@nl
type
label
Functional reconstitution of t ...... mediated by the TIM10 complex
@ast
Functional reconstitution of t ...... mediated by the TIM10 complex
@en
Functional reconstitution of t ...... mediated by the TIM10 complex.
@nl
altLabel
Functional reconstitution of t ...... mediated by the TIM10 complex
@en
prefLabel
Functional reconstitution of t ...... mediated by the TIM10 complex
@ast
Functional reconstitution of t ...... mediated by the TIM10 complex
@en
Functional reconstitution of t ...... mediated by the TIM10 complex.
@nl
P2093
P2860
P3181
P356
P1433
P1476
Functional reconstitution of t ...... mediated by the TIM10 complex
@en
P2093
D R Robinson
M A Vergnolle
P2860
P304
P3181
P356
10.1093/EMBOJ/20.15.4099
P407
P577
2001-08-01T00:00:00Z