A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria
about
Apolipoprotein O is mitochondrial and promotes lipotoxicity in heartSam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexesDetailed analysis of the human mitochondrial contact site complex indicate a hierarchy of subunitsQIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphologyMINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organizationThe Secret Life of Tethers: The Role of Tethering Factors in SNARE Complex RegulationMitochondrial targets for pharmacological intervention in human diseaseThe connection between inner membrane topology and mitochondrial functionPhospholipid transport via mitochondriaMitochondrial form and functionA splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in miceHierarchical modularity and the evolution of genetic interactomes across species.The GARP complex is required for cellular sphingolipid homeostasis.The conserved AAA-ATPase Msp1 confers organelle specificity to tail-anchored proteinsEndoplasmic reticulum-associated mitochondria-cortex tether functions in the distribution and inheritance of mitochondriaMitochondrial ClpX Activates a Key Enzyme for Heme Biosynthesis and Erythropoiesis.Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites.VPS13 regulates membrane morphogenesis during sporulation in Saccharomyces cerevisiae.Intramitochondrial transport of phosphatidic acid in yeast by a lipid transfer protein.Ste24p Mediates Proteolysis of Both Isoprenylated and Non-prenylated Oligopeptides.Chemogenetic E-MAP in Saccharomyces cerevisiae for Identification of Membrane Transporters Operating Lipid Flip FlopRole for two conserved intermembrane space proteins, Ups1p and Ups2p, [corrected] in intra-mitochondrial phospholipid trafficking.ER-mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13.Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architectureRole of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria.OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demandTransgenic overexpression of mitofilin attenuates diabetes mellitus-associated cardiac and mitochondria dysfunctionDisorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genesThe topology and regulation of cardiolipin biosynthesis and remodeling in yeastFunctional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactionsIL-15Rα deficiency in skeletal muscle alters respiratory function and the proteome of mitochondrial subpopulations independent of changes to the mitochondrial genomeMitochondria: in sickness and in healthThe presequence pathway is involved in protein sorting to the mitochondrial outer membrane.Analysis of mutations in Neurospora crassa ERMES components reveals specific functions related to β-barrel protein assembly and maintenance of mitochondrial morphology.Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane.The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria.Potential function for the Huntingtin protein as a scaffold for selective autophagy.Regulated membrane remodeling by Mic60 controls formation of mitochondrial crista junctionsAge-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondriaTransient contraction of mitochondria induces depolarization through the inner membrane dynamin OPA1 protein.
P2860
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P248
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P2860
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A mitochondrial-focused geneti ...... e organization in mitochondria
@ast
A mitochondrial-focused geneti ...... e organization in mitochondria
@en
A mitochondrial-focused geneti ...... organization in mitochondria.
@nl
type
label
A mitochondrial-focused geneti ...... e organization in mitochondria
@ast
A mitochondrial-focused geneti ...... e organization in mitochondria
@en
A mitochondrial-focused geneti ...... organization in mitochondria.
@nl
prefLabel
A mitochondrial-focused geneti ...... e organization in mitochondria
@ast
A mitochondrial-focused geneti ...... e organization in mitochondria
@en
A mitochondrial-focused geneti ...... organization in mitochondria.
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
A mitochondrial-focused geneti ...... e organization in mitochondria
@en
P2093
Ann Cassidy-Stone
Jodi Nunnari
Laura L Lackner
Rachel M Devay
Suzanne Hoppins
P2860
P304
P3181
P356
10.1083/JCB.201107053
P407
P577
2011-10-17T00:00:00Z