Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast
about
LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulumDerlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradationRecruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membraneMultiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane.Folding-competent and folding-defective forms of ricin A chain have different fates after retrotranslocation from the endoplasmic reticulumInhibition of p97-dependent protein degradation by Eeyarestatin IMurine polyomavirus requires the endoplasmic reticulum protein Derlin-2 to initiate infectionThe cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome systemMisfolded proteins are sorted by a sequential checkpoint mechanism of ER quality controlIRE1-independent gain control of the unfolded protein responseA molecular portrait of the response to unfolded proteinsCancer Microenvironment and Endoplasmic Reticulum Stress ResponseUbiquitylation of an ERAD substrate occurs on multiple types of amino acidsProtein folding and quality control in the ERSelective destruction of abnormal proteins by ubiquitin-mediated protein quality control degradationThe protein translocation channel mediates glycopeptide export across the endoplasmic reticulum membraneIn vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation.Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation.Sec61p is part of the endoplasmic reticulum-associated degradation machineryERAD and protein import defects in a sec61 mutant lacking ER-lumenal loop 7.The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation.The protein translocation channel binds proteasomes to the endoplasmic reticulum membraneDefining the glycan destruction signal for endoplasmic reticulum-associated degradationThe Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitmentAn HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transportThe ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48pDer3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins.Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulatorAutoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.Receptors determine the cellular localization of a gamma-tubulin complex and thereby the site of microtubule formation.Yos9p assists in the degradation of certain nonglycosylated proteins from the endoplasmic reticulumThe conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae.Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.Ubx4 modulates cdc48 activity and influences degradation of misfolded proteins of the endoplasmic reticulumDistinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding.AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation.A novel protein complex promoting formation of functional alpha- and gamma-tubulin.An unusual ERAD-like complex is targeted to the apicoplast of Plasmodium falciparumDissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin
P2860
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P2860
Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast
description
1996 nî lūn-bûn
@nan
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Der1, a novel protein specific ...... reticulum degradation in yeast
@ast
Der1, a novel protein specific ...... reticulum degradation in yeast
@en
Der1, a novel protein specific ...... eticulum degradation in yeast.
@nl
type
label
Der1, a novel protein specific ...... reticulum degradation in yeast
@ast
Der1, a novel protein specific ...... reticulum degradation in yeast
@en
Der1, a novel protein specific ...... eticulum degradation in yeast.
@nl
prefLabel
Der1, a novel protein specific ...... reticulum degradation in yeast
@ast
Der1, a novel protein specific ...... reticulum degradation in yeast
@en
Der1, a novel protein specific ...... eticulum degradation in yeast.
@nl
P2093
P2860
P3181
P1433
P1476
Der1, a novel protein specific ...... reticulum degradation in yeast
@en
P2093
P2860
P304
P3181
P407
P577
1996-02-15T00:00:00Z