Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains. - Test2 - elhamkhani - TriplyDB

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

http://www.wikidata.org/entity/Q27933866

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MAP kinase pathways in the yeast Saccharomyces cerevisiae The cyclophilins Calcineurin Orchestrates Hyphal Growth, Septation, Drug Resistance and Pathogenesis of Aspergillus fumigatus: Where Do We Go from Here?Functional analysis of the yeast 40 kDa cyclophilin Cyp40 and its role for viability and steroid receptor regulation.Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiae.The NH2-terminal extension of protein phosphatase PPZ1 has an essential functional role.FKBP12-rapamycin target TOR2 is a vacuolar protein with an associated phosphatidylinositol-4 kinase activity.Protein phosphatase type 1 regulates ion homeostasis in Saccharomyces cerevisiae.Cyclophilin A mediates Vid22p function in the import of fructose-1,6-bisphosphatase into Vid vesicles.Functions of FKBP12 and mitochondrial cyclophilin active site residues in vitro and in vivo in Saccharomyces cerevisiae vph6 mutants of Saccharomyces cerevisiae require calcineurin for growth and are defective in vacuolar H(+)-ATPase assembly.FKBP12 controls aspartate pathway flux in Saccharomyces cerevisiae to prevent toxic intermediate accumulation.Differential expression and function of two homologous subunits of yeast 1,3-beta-D-glucan synthase.All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae.Purification of FKBP-70, a novel immunophilin from Saccharomyces cerevisiae, and cloning of its structural gene, FPR3.Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action Synergistic antifungal activities of bafilomycin A(1), fluconazole, and the pneumocandin MK-0991/caspofungin acetate (L-743,873) with calcineurin inhibitors FK506 and L-685,818 against Cryptococcus neoformans Calcineurin is required for hyphal elongation during mating and haploid fruiting in Cryptococcus neoformans Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans The immunosuppressant FK506 and its nonimmunosuppressive analog L-685,818 are toxic to Cryptococcus neoformans by inhibition of a common target protein Calcineurin Targets Involved in Stress Survival and Fungal Virulence Detailed characterization of a cyclophilin from the human malaria parasite Plasmodium falciparum Frequency-modulated nuclear localization bursts coordinate gene regulation.CaZF, a plant transcription factor functions through and parallel to HOG and calcineurin pathways in Saccharomyces cerevisiae to provide osmotolerance.Rapamycin antifungal action is mediated via conserved complexes with FKBP12 and TOR kinase homologs in Cryptococcus neoformans.Calcium binding is required for calmodulin function in Aspergillus nidulans Alanine-scanning mutagenesis of protein phosphatase type 1 in the yeast Saccharomyces cerevisiae.Immunosuppressive and nonimmunosuppressive cyclosporine analogs are toxic to the opportunistic fungal pathogen Cryptococcus neoformans via cyclophilin-dependent inhibition of calcineurin The eukaryotic response regulator Skn7p regulates calcineurin signaling through stabilization of Crz1p.Calcineurin is essential for survival during membrane stress in Candida albicans.Calcineurin determines toxic versus beneficial responses to α-synuclein.Luv1p/Rki1p/Tcs3p/Vps54p, a yeast protein that localizes to the late Golgi and early endosome, is required for normal vacuolar morphology.Good fungi gone bad: the corruption of calcineurin.Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans.Calcineurin is essential for virulence in Candida albicans.A non-canonical RNA degradation pathway suppresses RNAi-dependent epimutations in the human fungal pathogen Mucor circinelloides.Characterization of calcineurin from Cryptococcus humicola and the application of calcineurin in aluminum tolerance.Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, is essential in yeast mutants with cell integrity defects and in mutants that lack a functional vacuolar H(+)-ATPase.Physiological roles of calcineurin in Saccharomyces cerevisiae with special emphasis on its roles in G2/M cell-cycle regulation.Calcineurin regulation in fungi and beyond

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P2860

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

http://www.wikidata.org/entity/Q27933866

description

1994 nî lūn-bûn

@nan

1994 թուականի Յունիսին հրատարակուած գիտական յօդուած

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1994 թվականի հունիսին հրատարակված գիտական հոդված

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1994年の論文

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1994年論文

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1994年論文

@zh-hant

1994年論文

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1994年論文

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1994年論文

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1994年论文

@wuu

name

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@ast

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@en

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@nl

type

label

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@ast

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@en

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@nl

prefLabel

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@ast

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@en

Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@nl

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PNAS.91.12.5372

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Proceedings of the National Academy of Sciences of the United States of America

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Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strains.

@en

P2093

C S Hemenway

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J Heitman

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M E Cardenas

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N R Movva

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T Breuder

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P2860

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

Molecular cloning and overexpression of the human FK506-binding protein FKBP

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase

Yeast cyclophilin: isolation and characterization of the protein, cDNA and gene.

FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae.

Rapamycin sensitivity in Saccharomyces cerevisiae is mediated by a peptidyl-prolyl cis-trans isomerase related to human FK506-binding protein

Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone.

Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein

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10.1073/PNAS.91.12.5372

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12

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7515500

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