Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes
about
Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast.Dynamic ubiquitination of the mitogen-activated protein kinase kinase (MAPKK) Ste7 determines mitogen-activated protein kinase (MAPK) specificity.Scaffold Protein Ahk1, Which Associates with Hkr1, Sho1, Ste11, and Pbs2, Inhibits Cross Talk Signaling from the Hkr1 Osmosensor to the Kss1 Mitogen-Activated Protein KinaseThe RACK1 ortholog Asc1 functions as a G-protein beta subunit coupled to glucose responsiveness in yeast.Dissecting genealogy and cell cycle as sources of cell-to-cell variability in MAPK signaling using high-throughput lineage tracking.Dynamically reshaping signaling networks to program cell fate via genetic controllersIdentifying functional mechanisms of gene and protein regulatory networks in response to a broader range of environmental stresses.Mitogen-activated protein kinases with distinct requirements for Ste5 scaffolding influence signaling specificity in Saccharomyces cerevisiaeSte11p MEKK signals through HOG, mating, calcineurin and PKC pathways to regulate the FKS2 geneMagnificent seven: roles of G protein-coupled receptors in extracellular sensing in fungi.Use of pleiotropy to model genetic interactions in a population.Regulated cell-to-cell variation in a cell-fate decision system.Mechanisms of MAPK signalling specificity.Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics.Neoplastic transformation induced by the gep oncogenes involves the scaffold protein JNK-interacting leucine zipper proteinMachines vs. ensembles: effective MAPK signaling through heterogeneous sets of protein complexes.Dynamic studies of scaffold-dependent mating pathway in yeast.Regulation of cell wall biogenesis in Saccharomyces cerevisiae: the cell wall integrity signaling pathway.Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK.Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiaeCombined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificityMembrane localization of scaffold proteins promotes graded signaling in the yeast MAP kinase cascade.Mechanisms and constraints on yeast MAPK signaling specificity.Global analysis of serine/threonine and tyrosine protein phosphatase catalytic subunit genes in Neurospora crassa reveals interplay between phosphatases and the p38 mitogen-activated protein kinase.GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression.Distinct docking mechanisms mediate interactions between the Msg5 phosphatase and mating or cell integrity mitogen-activated protein kinases (MAPKs) in Saccharomyces cerevisiaeThe Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae.G-protein signaling: a new branch in an old pathwayGlycosylation defects activate filamentous growth Kss1 MAPK and inhibit osmoregulatory Hog1 MAPK.Cdc24 regulates nuclear shuttling and recruitment of the Ste5 scaffold to a heterotrimeric G protein in Saccharomyces cerevisiae.Control of MAPK specificity by feedback phosphorylation of shared adaptor protein Ste50.Analysis of the thresholds for transcriptional activation by the yeast MAP kinases Fus3 and Kss1.Mapping regions in Ste5 that support Msn5-dependent and -independent nuclear export.Heritable stress response dynamics revealed by single-cell genealogy., a Gene Encoding a Putative Component of the RSC Chromatin Remodeling Complex, Is Involved in Hyphal Growth, Reactive Oxygen Species Accumulation, and Pathogenicity in
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P2860
Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Differential input by Ste5 sca ...... K cascade to multiple outcomes
@ast
Differential input by Ste5 sca ...... K cascade to multiple outcomes
@en
Differential input by Ste5 sca ...... cascade to multiple outcomes.
@nl
type
label
Differential input by Ste5 sca ...... K cascade to multiple outcomes
@ast
Differential input by Ste5 sca ...... K cascade to multiple outcomes
@en
Differential input by Ste5 sca ...... cascade to multiple outcomes.
@nl
prefLabel
Differential input by Ste5 sca ...... K cascade to multiple outcomes
@ast
Differential input by Ste5 sca ...... K cascade to multiple outcomes
@en
Differential input by Ste5 sca ...... cascade to multiple outcomes.
@nl
P2093
P2860
P356
P1433
P1476
Differential input by Ste5 sca ...... K cascade to multiple outcomes
@en
P2093
David M Simpson
Elaine A Elion
Jessica Andersson
Maosong Qi
Yunmei Wang
P2860
P304
P356
10.1038/SJ.EMBOJ.7600250
P407
P577
2004-07-07T00:00:00Z