Phosphatidylinositol 4-phosphate controls both membrane recruitment and a regulatory switch of the Rab GEF Sec2p.
about
RabGEFs are a major determinant for specific Rab membrane targetingArf GTPase regulation through cascade mechanisms and positive feedback loopsRegulation of small GTPases by GEFs, GAPs, and GDIsPhosphoinositides: tiny lipids with giant impact on cell regulationGTPase networks in membrane trafficGolgi membrane dynamics and lipid metabolismTracking individual secretory vesicles during exocytosis reveals an ordered and regulated process.The activation cycle of Rab GTPase Ypt32 reveals structural determinants of effector recruitment and GDI bindingStructures of PI4KIII complexes show simultaneous recruitment of Rab11 and its effectorsThe Msb3/Gyp3 GAP controls the activity of the Rab GTPases Vps21 and Ypt7 at endosomes and vacuolesGuanine nucleotide exchange factors (GEFs) have a critical but not exclusive role in organelle localization of Rab GTPases.Vps9 family protein Muk1 is the second Rab5 guanosine nucleotide exchange factor in budding yeast.Rabs and the exocyst in ciliogenesis, tubulogenesis and beyond.A Rab8 guanine nucleotide exchange factor-effector interaction network regulates primary ciliogenesisThe Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11-Rab8-mediated ciliary receptor targeting.Crosstalk of Arf and Rab GTPases en route to cilia.Cinderella story: PI4P goes from precursor to key signaling moleculeNDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15A detour for yeast oxysterol binding proteinsSecretory pathway-dependent localization of the Saccharomyces cerevisiae Rho GTPase-activating protein Rgd1p at growth sitesOsh4p is needed to reduce the level of phosphatidylinositol-4-phosphate on secretory vesicles as they mature.Dynamic association of the PI3P-interacting Mon1-Ccz1 GEF with vacuoles is controlled through its phosphorylation by the type 1 casein kinase Yck3.Maturation of late Golgi cisternae into RabE(RAB11) exocytic post-Golgi carriers visualized in vivo.Walking to work: roles for class V myosins as cargo transporters.Insights into the mechanisms of sterol transport between organelles.Coordination of Golgi functions by phosphatidylinositol 4-kinases.Activation of Rab8 guanine nucleotide exchange factor Rabin8 by ERK1/2 in response to EGF signalingSignaling at the Golgi.Membrane-trafficking sorting hubs: cooperation between PI4P and small GTPases at the trans-Golgi network.Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex.Phosphatidylinositol-4-phosphate-dependent membrane traffic is critical for fungal filamentous growth.Phosphoinositides and vesicular membrane trafficPhosphatidylserine Synthase Controls Cell Elongation Especially in the Uppermost Internode in Rice by Regulation of Exocytosis.Sbf/MTMR13 coordinates PI(3)P and Rab21 regulation in endocytic control of cellular remodeling.RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans.βIII spectrin regulates the structural integrity and the secretory protein transport of the Golgi complexThe casein kinases Yck1p and Yck2p act in the secretory pathway, in part, by regulating the Rab exchange factor Sec2p.Requirement of Phosphoinositides Containing Stearic Acid To Control Cell PolarityStructural basis of membrane trafficking by Rab family small G protein.Review series: Rab GTPases and membrane identity: causal or inconsequential?
P2860
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P2860
Phosphatidylinositol 4-phosphate controls both membrane recruitment and a regulatory switch of the Rab GEF Sec2p.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@ast
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@en
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@nl
type
label
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@ast
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@en
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@nl
prefLabel
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@ast
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@en
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@nl
P2093
P2860
P3181
P1433
P1476
Phosphatidylinositol 4-phospha ...... y switch of the Rab GEF Sec2p.
@en
P2093
Emi Mizuno-Yamasaki
Jeff Coleman
Martina Medkova
Peter Novick
P2860
P304
P3181
P356
10.1016/J.DEVCEL.2010.03.016
P407
P577
2010-05-18T00:00:00Z