The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism.
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Crystal structures of two human pyrophosphorylase isoforms in complexes with UDPGlc(Gal)NAc: role of the alternatively spliced insert in the enzyme oligomeric assembly and active site architecture.Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans and catalytic reaction mechanismStructure and Mutational Analysis of the Archaeal GTP:AdoCbi-P Guanylyltransferase (CobY) from Methanocaldococcus jannaschii: Insights into GTP Binding and DimerizationGenetic and structural validation ofAspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase as an antifungal targetSaccharomyces cerevisiae GNA1, an essential gene encoding a novel acetyltransferase involved in UDP-N-acetylglucosamine synthesis.Involvement of GFA1, which encodes glutamine-fructose-6-phosphate amidotransferase, in the activation of the chitin synthesis pathway in response to cell-wall defects in Saccharomyces cerevisiae.UDP-sugar pyrophosphorylase with broad substrate specificity toward various monosaccharide 1-phosphates from pea sproutsPlant-type trehalose synthetic pathway in cryptosporidium and some other apicomplexansKinetic and physical characterization of the inducible UDP-N-acetylglucosamine pyrophosphorylase from Giardia intestinalis.Identification and characterization of a strict and a promiscuous N-acetylglucosamine-1-P uridylyltransferase in Arabidopsis.Detecting network communities: an application to phylogenetic analysis.A cytoplasmic quaking I isoform regulates the hnRNP F/H-dependent alternative splicing pathway in myelinating glia.Reaction mechanism of phosphoglucosamine mutase from Escherichia coli.A 17-amino acid insert changes UDP-N-acetylhexosamine pyrophosphorylase specificity from UDP-GalNAc to UDP-GlcNAc.Molecular and functional analysis of UDP-N-acetylglucosamine Pyrophosphorylases from the Migratory Locust, Locusta migratoria.Functional inactivation of UDP-N-acetylglucosamine pyrophosphorylase 1 (UAP1) induces early leaf senescence and defence responses in ricePeracetylated 4-fluoro-glucosamine reduces the content and repertoire of N- and O-glycans without direct incorporation.A little sugar goes a long way: the cell biology of O-GlcNAc.Identification, subcellular localization, biochemical properties, and high-resolution crystal structure of Trypanosoma brucei UDP-glucose pyrophosphorylaseProteotranscriptomic Profiling of 231-BR Breast Cancer Cells: Identification of Potential Biomarkers and Therapeutic Targets for Brain Metastasis.Substrate-bound crystal structures reveal features unique to Mycobacterium tuberculosis N-acetyl-glucosamine 1-phosphate uridyltransferase and a catalytic mechanism for acetyl transfer.Purification, crystallization and preliminary X-ray diffraction studies of N-acetylglucosamine-phosphate mutase from Candida albicans.Purification, crystallization and preliminary X-ray diffraction studies of UDP-N-acetylglucosamine pyrophosphorylase from Candida albicans.Architecture and biosynthesis of the Saccharomyces cerevisiae cell wall.The synthesis of UDP-N-acetylglucosamine is essential for bloodstream form trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation.Cytoplasmic steps of peptidoglycan biosynthesis.Peptidoglycan biosynthesis machinery: a rich source of drug targets.Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target.Characterization of N-Acetylglucosamine Biosynthesis in Pneumocystis species. A New Potential Target for Therapy.acs1 of Haemophilus influenzae type a capsulation locus region II encodes a bifunctional ribulose 5-phosphate reductase- CDP-ribitol pyrophosphorylase.PKA, PHO and stress response pathways regulate the expression of UDP-glucose pyrophosphorylase through Msn2/4 in budding yeast.Up-regulation of genes involved in N-acetylglucosamine uptake and metabolism suggests a recycling mode of chitin in intraradical mycelium of arbuscular mycorrhizal fungi.Mummy, A UDP-N-acetylglucosamine pyrophosphorylase, modulates DPP signaling in the embryonic epidermis of Drosophila.Dissection of the bifunctional Escherichia coli N-acetylglucosamine-1-phosphate uridyltransferase enzyme into autonomously functional domains and evidence that trimerization is absolutely required for glucosamine-1-phosphate acetyltransferase activiIdentification and characterization of the genes for N-acetylglucosamine kinase and N-acetylglucosamine-phosphate deacetylase in the pathogenic fungus Candida albicans.A bifunctional enzyme with L-fucokinase and GDP-L-fucose pyrophosphorylase activities salvages free L-fucose in Arabidopsis.The glycosylation pathway is required for the secretion of Slit and for the maintenance of the Slit receptor Robo on axons.Glycosylation deficiency phenotypes resulting from depletion of GDP-mannose pyrophosphorylase in two yeast species.Properties and physiological functions of UDP-sugar pyrophosphorylase in Arabidopsis.N-acetylglucosamine-1-P uridylyltransferase 1 and 2 are required for gametogenesis and embryo development in Arabidopsis thaliana.
P2860
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P2860
The eukaryotic UDP-N-acetylglucosamine pyrophosphorylases. Gene cloning, protein expression, and catalytic mechanism.
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@ast
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@en
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@nl
type
label
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@ast
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@en
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@nl
prefLabel
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@ast
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@en
The eukaryotic UDP-N-acetylglu ...... sion, and catalytic mechanism.
@nl
P2093
P2860
P356
P1476
The eukaryotic UDP-N-acetylglu ...... ssion, and catalytic mechanism
@en
P2093
P2860
P304
14392-14397
P356
10.1074/JBC.273.23.14392
P407
P50
P577
1998-06-01T00:00:00Z