Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination.
about
Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factorsMechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loopsFunctional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separationA tale of tails: insights into the coordination of 3' end processing during homologous recombinationInvolvement of nucleotide excision and mismatch repair mechanisms in double strand break repairA MutSβ-Dependent Contribution of MutSα to Repeat Expansions in Fragile X Premutation Mice?Postreplicative mismatch repair.Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairsRole of Saw1 in Rad1/Rad10 complex assembly at recombination intermediates in budding yeastNew insights into the mechanism of DNA mismatch repairMlh1-Mlh3, a meiotic crossover and DNA mismatch repair factor, is a Msh2-Msh3-stimulated endonucleaseMsh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiaeThe mismatch repair and meiotic recombination endonuclease Mlh1-Mlh3 is activated by polymer formation and can cleave DNA substrates in trans.Eukaryotic Mismatch Repair in Relation to DNA ReplicationCruciform structures are a common DNA feature important for regulating biological processes.The nucleotide binding dynamics of human MSH2-MSH3 are lesion dependentDNA curtains and nanoscale curtain rods: high-throughput tools for single molecule imaging.Hijacking of the mismatch repair system to cause CAG expansion and cell death in neurodegenerative disease.Saccharomyces cerevisiae MSH2-MSH3 and MSH2-MSH6 complexes display distinct requirements for DNA binding domain I in mismatch recognition.Chimeric Saccharomyces cerevisiae Msh6 protein with an Msh3 mispair-binding domain combines properties of both proteins.Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples.Evidence that the DNA mismatch repair system removes 1-nucleotide Okazaki fragment flaps.The unstructured linker arms of Mlh1-Pms1 are important for interactions with DNA during mismatch repair.Msh2-Msh3 interferes with Okazaki fragment processing to promote trinucleotide repeat expansions.Dynamic DNA binding licenses a repair factor to bypass roadblocks in search of DNA lesions.Interconverting conformations of slipped-DNA junctions formed by trinucleotide repeats affect repair outcomeSequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast.Mutants defective in Rad1-Rad10-Slx4 exhibit a unique pattern of viability during mating-type switching in Saccharomyces cerevisiae.The mismatch repair system promotes DNA polymerase zeta-dependent translesion synthesis in yeast.Evidence that msh1p plays multiple roles in mitochondrial base excision repair.Structural insights into Saccharomyces cerevisiae Msh4-Msh5 complex function using homology modelingMispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex.Multiple factors insulate Msh2-Msh6 mismatch repair activity from defects in Msh2 domain I.Structural and functional analysis of the MutS C-terminal tetramerization domain.Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei.ATP binding and hydrolysis by Saccharomyces cerevisiae Msh2-Msh3 are differentially modulated by mismatch and double-strand break repair DNA substrates.Distinct requirements within the Msh3 nucleotide binding pocket for mismatch and double-strand break repair.mlh3 mutations in baker's yeast alter meiotic recombination outcomes by increasing noncrossover events genome-wide.Up-regulation of mismatch repair genes MSH6, PMS2 and MLH1 parallels development of genetic instability and is linked to tumor aggressiveness and early PSA recurrence in prostate cancer.Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair.
P2860
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P2860
Mismatch repair factor MSH2-MSH3 binds and alters the conformation of branched DNA structures predicted to form during genetic recombination.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@ast
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@en
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@nl
type
label
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@ast
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@en
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@nl
prefLabel
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@ast
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@en
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@nl
P921
P3181
P1476
Mismatch repair factor MSH2-MS ...... during genetic recombination.
@en
P2093
Eric Alani
Jennifer A Surtees
P304
P3181
P356
10.1016/J.JMB.2006.05.032
P407
P577
2006-07-14T00:00:00Z