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Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferaseHuman bocavirus capsid structure: insights into the structural repertoire of the parvoviridaeNon-Classical Inhibition of Carbonic AnhydrasePolylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolutionKinetic analysis of multiple proton shuttles in the active site of human carbonic anhydraseThe refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transferStructure of human carnitine acetyltransferase. Molecular basis for fatty acyl transferAtomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanismSpeeding up proton transfer in a fast enzyme: kinetic and crystallographic studies on the effect of hydrophobic amino acid substitutions in the active site of human carbonic anhydrase IIStructural and kinetic analysis of proton shuttle residues in the active site of human carbonic anhydrase IIIApo-Human Carbonic Anhydrase II Revisited: Implications of the Loss of a Metal in Protein Structure, Stability, and Solvent Network ,Structure of Adeno-Associated Virus Serotype 8, a Gene Therapy VectorStructural and kinetic study of differences between human and Escherichia coli manganese superoxide dismutasesThe contribution of naturally occurring polymorphisms in altering the biochemical and structural characteristics of HIV-1 subtype C proteaseDesign, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutationInhibition of carbonic anhydrase II by thioxolone: a mechanistic and structural studyRole of a glutamate bridge spanning the dimeric interface of human manganese superoxide dismutaseHigh-resolution structure of unbound human immunodeficiency virus 1 subtype C protease: implications of flap dynamics and drug resistanceEntrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase IIRole of Hydrophilic Residues in Proton Transfer during Catalysis by Human Carbonic Anhydrase II † ‡Structure determination of the cancer-associated Mycoplasma hyorhinis protein Mh-p37Design of a Carbonic Anhydrase IX Active-Site Mimic To Screen Inhibitors for Possible Anticancer Properties † ‡Structural Insights into the Extracytoplasmic Thiamine-Binding Lipoprotein p37 of Mycoplasma hyorhinisCrystallographic evidence for noncoplanar catalytic aspartic acids in plasmepsin II resides in the Protein Data BankRecombinant Plasmepsin 1 from the Human Malaria Parasite Plasmodium falciparum : Enzymatic Characterization, Active Site Inhibitor Design, and Structural AnalysisHigh-resolution structure of human carbonic anhydrase II complexed with acetazolamide reveals insights into inhibitor drug designA Short, Strong Hydrogen Bond in the Active Site of Human Carbonic Anhydrase IIStructure of the unbound form of HIV-1 subtype A protease: comparison with unbound forms of proteases from other HIV subtypesStructural and Kinetic Study of the Extended Active Site for Proton Transfer in Human Carbonic Anhydrase IICoumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigationsCarbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitorsComparison of solution and crystal properties of Co(II)–substituted human carbonic anhydrase IIEmerging from pseudo-symmetry: the redetermination of human carbonic anhydrase II in monoclinicP21with a doubledaaxisStructural Characterization of the Dual Glycan Binding Adeno-Associated Virus Serotype 6Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potencySynchrotron Radiation Provides a Plausible Explanation for the Generation of a Free Radical Adduct of Thioxolone in Mutant Carbonic Anhydrase IIInsights into Mycoplasma genitalium metabolism revealed by the structure of MG289, an extracytoplasmic thiamine binding lipoproteinKinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase IIAnticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIVSulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies
P50
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P50
description
hulumtues
@sq
onderzoeker
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researcher
@en
հետազոտող
@hy
name
Robert McKenna
@ast
Robert McKenna
@en
Robert McKenna
@es
Robert McKenna
@sl
type
label
Robert McKenna
@ast
Robert McKenna
@en
Robert McKenna
@es
Robert McKenna
@sl
prefLabel
Robert McKenna
@ast
Robert McKenna
@en
Robert McKenna
@es
Robert McKenna
@sl